Defactinib - Moligand™, 10 mM in DMSO , CAS No.1073154-85-4

CAS: 1073154-85-4 Cat. No.: D1495477 Summenformel: C₂₀H₂₁F₃N₈O₃S Molekulargewicht: 510.49 EG-Nummer: 969-109-7

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Defactinib (VS-6063; PF-04554878) is a novel FAK inhibitor with potential antiangiogenic and antineoplastic activities.

Specifications

Spezifikationen & Reinheit

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

INHIBITOR

Produkteigenschaften

• ALogP: 1.4

Namen und Kennungen

• Isomere SMILES: CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F
• Alternative CAS-Nummer: 1073154-85-4
• MeSH-Eintrag: defactinib;N-methyl-4-((4-(((3-methyl(methylsulfonyl)aminopyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide;PF-04554878;VS-6063
• Molekulargewicht: 510.49
• Reaxy-Rn: 18939458
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18939458&ln=

Referenzen

1. Zhou Hao, Wang Wei, Cai Zedong, Jia Zhou-Yan, Li Yu-Yao, He Wei, Li Chen, Zhang Bang-Le.  (2024)  Injectable hybrid hydrogels enable enhanced combination chemotherapy and roused anti-tumor immunity in the synergistic treatment of pancreatic ductal adenocarcinoma.  JOURNAL OF NANOBIOTECHNOLOGY,  22  (1): (1-21).  [PMID:38902759] [10.1186/s12951-024-02646-7]

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1073154-85-4, the molecular formula is C20H21F3N8O3S, and the molecular weight is 510.49 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.