Dexamethasone Solution (10mM) - BioReagent, for Cell culture, Sterile, 10 mM in DMSO , CAS No.50-02-2

CAS: 50-02-2 Cat. No.: C1524668 Summenformel: C₂₂H₂₉FO₅ Molekulargewicht: 392.46 Beilstein Registry Number: 2066651 EG-Nummer: 200-003-9

QUALITÄT & REINHEIT BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Synonyms

Dexamethasone Solution | DEX | DXM

Storage

Store at 2-8°C,Do not freeze

Shipped In

Wet ice

Übersicht

Dexamethasone is an adrenocortical hormone substance with multiple pharmacological effects including anti‑inflammatory, anti‑allergic, immunosuppressive and anti‑shock activities. It exerts certain physiological effects on cell culture, cell signal transduction and gene expression. Dexamethasone can induce disorder of hepatic glucose and lipid metabolism; inhibit the activation of the PI3K/Akt pathway and trigger osteoblast apoptosis; elevate intracellular ROS levels and mitochondrial superoxide production. It also induces the differentiation of human mesenchymal stem cells (MSCs), triggers autophagy in B‑cell acute lymphoblastic leukemia (B‑ALL), down‑regulates activated NF‑κB levels in immature dendritic cells (DCs), and suppresses their differentiation into mature DCs.

Dexamethasone Solution is a cell‑culture‑grade 10 mM stock solution. Researchers may dilute it at an appropriate ratio according to experimental requirements prior to direct use.

Product Properties:

CAS NO.: 50‑02‑2

Formula: C₂₂H₂₉FO₅

Molecular weight: 392.461

Appearance: Colorless transparent solution

Solubility: Soluble in ethanol and DMSO, slightly soluble in water

Melting point: 255～264 °C

Structure:

Precautions:

1. For your safety and health, please wear a lab coat and disposable gloves during operation.

2. This reagent is for research use only.

Spezifikationen

Synonyme

Dexamethasone Solution | DEX | DXM

Spezifikationen & Reinheit

BioReagent, for Cell culture, Sterile, 10 mM in DMSO

Stabilität und Lagerung

Store at 2-8°C long term (24 months). Store in the dark.

Storage

Store at 2-8°C,Do not freeze

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

BioReagent, für die Zellkultur, Sterile

Product Line

Biologische Produkte

Produkteigenschaften

ALogP

1.9

Namen und Kennungen

Isomere SMILES

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C

WGK Deutschland

2

RTECS

TU3980000

Alternative CAS-Nummer

23495-06-9,50-02-2

NSC-Nummer

34521

MeSH-Eintrag

Decaject;Decaject L.A.;Decaject-L.A.;Decameth;Decaspray;Dexamethasone;Dexasone;Dexpak;Hexadecadrol;Hexadrol;Maxidex;Methylfluorprednisolone;Millicorten;Oradexon

Molekulargewicht

392.46

Beilstein

2066651

Reaxy-Rn

2341697

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2341697&ln=

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in ethanol and DMSO, slightly soluble in water
• Schmelzpunkt (°C): 262-264°C