Dextranase from Chaetomium erraticum, CAS No.9025-70-1

CAS: 9025-70-1 Cat. No.: D298997 EG-Nummer: 232-803-9 PubChem CID: 135273372

GRADE & PURITY EnzymoPure™, ≥100 KDU-A/g

Bioactivity

≥100 KDU-A/g

Übersicht

Dextranase hydrolyzes the (1,6)-alpha-D-glucosidic linkages in dextran.

This product is a fungal dextranase produced by submerged fermentation of Chaetomium erraticum.

It has many industrial and clinical applications such as food processing, sugar modification, and medicine preparation. Dextranase is widely used to produce alternated sugar beet and isomaltooligosaccharides (IMOs), a prebiotic functional food. The low molecular weight dextran obtained from dextranase serves as a synthetic blood volume expander. Dextranase can be coupled to antibodies for the detection of tumor cells. It prevents the occurrence of dental plaques by depolymerizing microbial dextran deposits in teeth. Hence, it is used in dental care products.

Stable in the pH range of 3-7 and at temperatures up to approx. 70 °C. For most applications, the preferred conditions are pH 5-6 and a temperature of 50-60 °C.

Application

Dextranase from Chaetomium erraticum has been used:

in microcarrier dissolution to produce multicellular 3D spheroids for drug discovery,

in in vitro digestion of extracellular polysaccharide (EPS) from the bacterial isolates,

in a study to investigate the immobilization of dextranase,

to investigate the optimization of process conditions for enzymatic modification of alternan.

Genetic Modification Status

This product is not a genetically modified organism (GMO).

Enzyme preparations are produced by microbial fermentation, with no residual microorganisms in the final product. The microorganisms used for production have not been modified by modern biotechnology.

Storage Conditions

Storage temperature: 2–8℃.

The original packaging must be kept intact during storage. Store in a dry environment and avoid direct sunlight.

Use the product in accordance with the recommended usage and prior to the expiration date of the shelf life to avoid the need for increased dosage.

Safety and Handling Precautions

Enzymes are proteins. Inhalation of dust or aerosols may cause sensitization and trigger allergic reactions in sensitized individuals.

Prolonged contact with some enzymes may cause irritation to the skin, eyes and mucous membranes.

Specifications

Product Name

Dextranase from Chaetomium erraticum, CAS No.9025-70-1

Synonyme

Dextranase Plus L | 1,6-α-D-Glucan 6-glucanohydrolase | Sustine 470

Note

EnzymoPure™

Spezifikationen & Reinheit

EnzymoPure™, ≥100 KDU-A/g

Bioaktivität

≥100 KDU-A/g

CAS

9025-70-1

Enzym Kommissionsnummer

EC 3.2.1.11

Molekültyp

Enzyme

Rechtliche Informationen

Dextranase Plus L of Novozymes Corp.

Lagerung und Versand

Konzentration

≥100 KDU-A/g

Storage

Store at 2-8°C

Verschickt in

Wet ice

Stabilität und Lagerung

Store at 2-8℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. Desiccated.

Definition der Einheit

One KDU-A is defined as the amount of enzyme required to hydrolyze dextran to produce 1 gram of maltose-equivalent reducing sugars per hour under the Novozymes standard assay conditions.