≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Sodium 3,5-dichloro-2-hydroxybenzenesulfonate is used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of uric acid in serum and urine samples.
| Pubchem Sid | 504762450 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504762450 |
| Canonical Smiles | C1=C(C=C(C(=C1S(=O)(=O)[O-])O)Cl)Cl.[Na+] |
| IUPAC Name | sodium;3,5-dichloro-2-hydroxybenzenesulfonate |
| InChIKey | NMWCVZCSJHJYFW-UHFFFAOYSA-M |
| INCHI | 1S/C6H4Cl2O4S.Na/c7-3-1-4(8)6(9)5(2-3)13(10,11)12;/h1-2,9H,(H,10,11,12);/q;+1/p-1 |
| Isomeric SMILES | C1=C(C=C(C(=C1S(=O)(=O)[O-])O)Cl)Cl.[Na+] |
| WGK Germany | 3 |
| PubChem CID | 3085077 |
| Molecular Weight | 265.05 |
| Beilstein | 3640643 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Benzenesulfonic acids and derivatives |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzenesulfonic acids and derivatives |
| Alternative Parents | Benzenesulfonyl compounds 1-sulfo,2-unsubstituted aromatic compounds P-chlorophenols O-chlorophenols Dichlorobenzenes Aryl chlorides Sulfonyls Organosulfonic acids Organic metal halides Organooxygen compounds Organochlorides Organic sodium salts Organic oxides Hydrocarbon derivatives Organic cations |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Benzenesulfonate - Arylsulfonic acid or derivatives - Benzenesulfonyl group - 1-sulfo,2-unsubstituted aromatic compound - 1,3-dichlorobenzene - 4-halophenol - 2-halophenol - 2-chlorophenol - 4-chlorophenol - Chlorobenzene - Halobenzene - Phenol - Aryl halide - Aryl chloride - Organosulfonic acid - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Sulfonyl - Organic metal halide - Organic alkali metal salt - Organic salt - Organic sodium salt - Organohalogen compound - Organochloride - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organosulfur compound - Organic oxygen compound - Organic cation - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as benzenesulfonic acids and derivatives. These are organic compounds containing a sulfonic acid or a derivative thereof that is linked to a benzene ring. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2612003 | Certificate of Analysis | Jun 27, 2026 | D109083 |
| F2228237 | Certificate of Analysis | Apr 02, 2026 | D109083 |
| F2228238 | Certificate of Analysis | Apr 02, 2026 | D109083 |
| J2128669 | Certificate of Analysis | Aug 11, 2025 | D109083 |
| C2531136 | Certificate of Analysis | Dec 13, 2024 | D109083 |
| C2531137 | Certificate of Analysis | Dec 13, 2024 | D109083 |
| F2228226 | Certificate of Analysis | Apr 29, 2022 | D109083 |
| H2402044 | Certificate of Analysis | Apr 29, 2022 | D109083 |
| D2408087 | Certificate of Analysis | Oct 16, 2021 | D109083 |
| J2422281 | Certificate of Analysis | Oct 16, 2021 | D109083 |
| Sensitivity | Hygroscopic |
|---|---|
| Molecular Weight | 265.050 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 263.903 Da |
| Monoisotopic Mass | 263.903 Da |
| Topological Polar Surface Area | 85.800 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 278.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
| 1. Junjun Wang, Yue Tang, Jia Zheng, Zhengmin Xie, Jianli Zhou, Yuangen Wu. (2023) DNAzyme-based and smartphone-assisted colorimetric biosensor for ultrasensitive and highly selective detection of histamine in meats. FOOD CHEMISTRY, [PMID:37742463] [10.1016/j.foodchem.2023.137526] |
| 2. Jie Li, Youcai Lu, Shiyu Ma, Zhongjun Li, Qingchao Liu. (2022) Covalent S and Cl grafted porous carbon host realized via the one-step pyrolysis method results in boosted Li–O2 battery performances. ELECTROCHIMICA ACTA, [PMID:] [10.1016/j.electacta.2022.140216] |
| 3. Jia Xu, Habib Khan, Li Yang. (2021) Hydrogel Paper-Based Analytical Devices: Separation-Free In Situ Assay of Small-Molecule Targets in Whole Blood. ANALYTICAL CHEMISTRY, [PMID:34709797] [10.1021/acs.analchem.1c03347] |
| 4. Li Fang, Hu Yuting, Zhao Anqi, Xi Yachao, Li Zimu, He Jianbao. (2020) β-Cyclodextrin coated porous Pd@Au nanostructures with enhanced peroxidase-like activity for colorimetric and paper-based determination of glucose. MICROCHIMICA ACTA, 187 (8): (1-11). [PMID:32623601] [10.1007/s00604-020-04410-8] |
| 5. He Shao-Bin, Chen Rui-Ting, Wu Yan-Yu, Wu Gang-Wei, Peng Hua-Ping, Liu Ai-Lin, Deng Hao-Hua, Xia Xing-Hua, Chen Wei. (2019) Improved enzymatic assay for hydrogen peroxide and glucose by exploiting the enzyme-mimicking properties of BSA-coated platinum nanoparticles. MICROCHIMICA ACTA, 186 (12): (1-9). [PMID:31728642] [10.1007/s00604-019-3939-y] |
| 6. Fang Li, Xu Wang, Jiachang Liu, Yuting Hu, Jianbo He. (2019) Double-layered microfluidic paper-based device with multiple colorimetric indicators for multiplexed detection of biomolecules. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2019.02.116] |
| 7. Wang Xu, Li Fang, Cai Ziqi, Liu Kaifan, Li Jing, Zhang Boyang, He Jianbo. (2018) Sensitive colorimetric assay for uric acid and glucose detection based on multilayer-modified paper with smartphone as signal readout. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 410 (10): (2647-2655). [PMID:29455281] [10.1007/s00216-018-0939-4] |
| 8. Lian Xia, Feng Luo, Xiaojuan Niu, Yue Tang, Yuangen Wu. (2024) Facile colorimetric sensor using oxidase-like activity of octahedral Ag2O particles for highly selective detection of Pb(II) in water. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:38219997] [10.1016/j.scitotenv.2024.170025] |
| 9. Cuicui Wang, Qing Xue, Haiqin Li, Hao Qi, Xiaochun Li. (2024) Urine multi-index intelligent detection based on polymer/paper hybrid microfluidic biochip for hyperuricemia monitoring. ANALYTICA CHIMICA ACTA, [PMID:38834261] [10.1016/j.aca.2024.342742] |
| 10. Jing Yang, Xiaoye Feng, Haiqin Li, Pengtao Chang, Xiaojun Ren, Xiaochun Li. (2025) Microfluidic Chip with Integrated Whole Blood Separation for Simultaneous Accurate Quantification of Multiple Chronic Kidney Disease Markers and Long-Term Monitoring. ACS Sensors, [PMID:40814749] [10.1021/acssensors.5c00491] |
