DHFR-IN-22 , CAS No.2941327-87-1

CAS: 2941327-87-1 Cat. No.: D1416024 Summenformel: C₂₂H₃₀N₄O₄ Molekulargewicht: 414.50

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

DHFR-IN-22 (Compound 8) is a DHFR ( Dihydrofolate Reductase ) inhibitor belonging to the class of 2,4-diaminopyrimidine compounds. DHFR-IN-22 exhibits significant inhibitory activity against purified DHFR enzyme and major species of nontuberculous mycobacteria (NTM), namely Mycobacterium avium and Mycobacterium abscessus. It shows an IC 50 of 1.1 nM and MIC of 1.5 μg/mL against M. abscessus , and an IC 50 of 6.3 nM and MIC of 0.1 μg/mL against M. avium. Additionally, it demonstrates an IC 50 of 2100 nM against human DHFR. DHFR-IN-22 holds potential for studying novel strategies to combat NTM infections.

Spezifikationen

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

Molekulargewicht

414.50

Häufig gestellte Fragen

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2941327-87-1, the molecular formula is C22H30N4O4, and the molecular weight is 414.50 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.