Dihomo-γ-linolenylethanolamide - Moligand™, Solution in ethanol , CAS No.150314-34-4

CAS: 150314-34-4 Cat. No.: D335501 Summenformel: C₂₂H₃₉NO₂ Molekulargewicht: 349.55

GRADE & PURITY Moligand™, Solution in ethanol

Synonyms

Dihomo-gamma-linolenoyl-EA | Dihomo-gamma-linolenoylethanolamide | 8,11,14-Eicosatrienoylethanolamide | BRD-K78280988-001-02-2 | HGLEA | Q27087920 | Dihomo- gamma -linolenylethanolamide | 8,11,14-Eicosatrienamide, N-(2-hydroxyethyl)-, (Z,Z,Z)- | ANA(20:3)

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Dihomo-γ-linolenylethanolamide is an endocannabinoid. Binds to recombinant human CB1 (K|i|= 857 nM) and CB2 receptor (K|i|= 598nM). Also inhibits adenylyl cyclase (IC|50|=109 nM).

Specifications

Synonyme

Dihomo-gamma-linolenoyl-EA | Dihomo-gamma-linolenoylethanolamide | 8,11,14-Eicosatrienoylethanolamide | BRD-K78280988-001-02-2 | HGLEA | Q27087920 | Dihomo- gamma -linolenylethanolamide | 8,11,14-Eicosatrienamide, N-(2-hydroxyethyl)-, (Z,Z,Z)- | ANA(20:3)

Spezifikationen & Reinheit

Moligand™, Solution in ethanol

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Namen und Kennungen

Kanonisches Lächeln

CCCCCC=CCC=CCC=CCCCCCCC(=O)NCCO

IUPAC Name

(8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-8,11,14-trienamide

InChIKey

ULQWKETUACYZLI-QNEBEIHSSA-N

INCHI

1S/C22H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,24H,2-5,8,11,14-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-

Isomere SMILES

CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)NCCO

Molekulargewicht

349.55

Reaxy-Rn

31590046

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31590046&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Klasse Organonitrogen compounds
      • Subclass Amines
        • Ebene5 Alkanolamines
          • Ebene6 1,2-aminoalcohols
            • Ebene7 N-acylethanolamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Klasse: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Alkanolamines - 1,2-aminoalcohols
• Direct Parent: N-acylethanolamines
• Alternative Parents: N-acyl amines Secondary carboxylic acid amides Primary alcohols Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: N-acylethanolamine - Fatty amide - N-acyl-amine - Fatty acyl - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Alcohol - Organooxygen compound - Primary alcohol - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as n-acylethanolamines. These are compounds containing an N-acyethanolamine moiety, which is characterized by an acyl group is linked to the nitrogen atom of ethanolamine.
• External Descriptors: N-acyl ethanolamines (endocannabinoids)

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

CNR1 Tclin Cannabinoid receptor 1 (1 Activities)

Discover Target: CNR1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)

Discover Target: CNR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Zugehörige Ziele (nicht menschlich)

RAW264.7 (28094 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RBL-2H3 (1162 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in DMSO (30mg/ml) or dimethyl formamide (10mg/ml); 8mg/ml soluble in a 1:2 solution of ethanol:PBS (pH 7.2) (dilute the ethanol solution with PBS).
• Siedepunkt (°C): ~508.04° C (Predicted)
• Molekulargewicht: 349.500 g/mol
• XLogP3: 6.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 17
• Exact Mass: 349.298 Da
• Monoisotopic Mass: 349.298 Da
• Topological Polar Surface Area: 49.300 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 372.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 3
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 3
• Covalently-Bonded Unit Count: 1

Häufig gestellte Fragen

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 150314-34-4, the molecular formula is C22H39NO2, and the molecular weight is 349.55 g/mol. InChIKey ULQWKETUACYZLI-QNEBEIHSSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.