Diltiazem - ≥99% , Voltage-gated L-type calcium channel blocker, CAS No.33286-22-5, Voltage-gated L-type calcium channel blocker

Name: Diltiazem - ≥99% , Voltage-gated L-type calcium channel blocker, CAS No.33286-22-5, Voltage-gated L-type calcium channel blocker
Brand: Aladdin Scientific
SKU: D276586
Availability: InStock

CAS: 33286-22-5 Cat. No.: D276586 Summenformel: C₂₂H₂₆N₂O₄S·HCl Molekulargewicht: 450.98 EG-Nummer: 251-443-3

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QUALITÄT & REINHEIT ≥99%

Synonyms

Storage

Room temperature

Shipped In

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Übersicht Spezifikationen Namen und Kennungen Dokumentation Erweiterte Daten Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Citations of This Product Lösungsrechner Bewertungen

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Warum diese Qualität

≥99% für empfindliche chromatographische und analytische Workflows, die minimale Basislinieninterferenzen erfordern.

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Lagerung & Versand

Room temperature Versand Normal. Genaue Spezifikationen finden Sie im chargenspezifischen COA.

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SDS, COA, Datenblatt und Spezifikationsblatt stehen zum Download bereit. Chargenspezifische COA über Chargennummernsuche abrufbar.

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Literaturbeleg

In 1 peer-reviewten Publikationen zu Chromatographie, organischer Synthese und Kreuzkupplungsreaktionen zitiert.

Übersicht

Store at Room Temperature. The product can be stored for up to 12 months.

Spezifikationen

Synonyme

Spezifikationen & Reinheit

≥99%

Biochemische und physiologische Mechanismen

L-type Ca 2+ channel antagonist. Coronary vasodilator. Soluble in 1 ml water to give specified mM/ml concentration. Find out more.

Storage

Room temperature

Verschickt in

Normal

Aktionsart

BLOCKER

Mechanismus der Wirkung

Voltage-gated L-type calcium channel blocker

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥99%

Namen und Kennungen

Kanonisches Lächeln

CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl

IUPAC Name

[(2S,3S)-5-[2-(dimethylamino)ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate;hydrochloride

InChIKey

HDRXZJPWHTXQRI-BHDTVMLSSA-N

INCHI

1S/C22H26N2O4S.ClH/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3;/h5-12,20-21H,13-14H2,1-4H3;1H/t20-,21+;/m1./s1

Isomere SMILES

CC(=O)O[C@@H]1[C@@H](SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC.Cl

WGK Deutschland

RTECS

DL0310000

Alternative CAS-Nummer

42399-41-7

Molekulargewicht

450.98

Reaxy-Rn

6889420

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6889420&ln=

Dokumentation

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Erweiterte Daten

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Klasse Benzothiazepines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Klasse	Benzothiazepines
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Benzothiazepines
Alternative Parents	Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Alkylarylthioethers Tertiary carboxylic acid amides Trialkylamines Lactams Amino acids and derivatives Carboxylic acid esters Monocarboxylic acids and derivatives Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Hydrochlorides Organic oxides Organopnictogen compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Benzothiazepine - Anisole - Phenol ether - Methoxybenzene - Aryl thioether - Phenoxy compound - Alkyl aryl ether - Alkylarylthioether - Monocyclic benzene moiety - Benzenoid - Tertiary carboxylic acid amide - Amino acid or derivatives - Carboxamide group - Tertiary aliphatic amine - Carboxylic acid ester - Tertiary amine - Lactam - Azacycle - Carboxylic acid derivative - Thioether - Ether - Monocarboxylic acid or derivatives - Organic oxygen compound - Hydrocarbon derivative - Hydrochloride - Carbonyl group - Organic nitrogen compound - Organopnictogen compound - Amine - Organic oxide - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as benzothiazepines. These are organic compounds containing a benzene fused to a thiazepine ring (a seven-membered ring with a nitrogen atom and a sulfur atom replacing two carbon atoms).
External Descriptors	hydrochloride
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

Zugehörige Ziele (menschlich)

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

U2OS (164939 Activities)

Löslichkeit	Soluble in\xa01ml of water\xa0to give specified mM/ml concentration
Spezifische Drehung [α]	114 to 122 deg(C=1, H2O)
Schmelzpunkt (°C)	210 °C
Molekulargewicht	451.000 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Exact Mass	450.138 Da
Monoisotopic Mass	450.138 Da
Topological Polar Surface Area	84.400 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	565.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Diltiazem - ≥99% , Voltage-gated L-type calcium channel blocker, CAS No.33286-22-5, Voltage-gated L-type calcium channel blocker

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