Diosgenine - ≥95% , CAS No.512-04-9

Name: Diosgenine - ≥95% , CAS No.512-04-9
SKU: D101265
Availability: InStock

CAS: 512-04-9 Cat. No.: D101265 Summenformel: C₂₇H₄₂O₃ Molekulargewicht: 414.62 Beilstein Registry Number: 94582 EG-Nummer: 208-134-3

15 Citations COA

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GRADE & PURITY ≥95%

Synonyms

(3beta,25R)-spirost-5-en-3-ol | AKOS015961083 | DIOSGENIN | (25R)-5-Spirosten-3A-ol | K49P2K8WLX | MFCD00016887 | DIOSGENIN [MI] | (1'S,2R,2'S,4'S,5R,7'S,8'R,9'S,12'S,13'R,16'S)-5,7',9',13'-tetramethyl-5'-oxaspiro[oxane-2,6'-pentacyclo[10.8.0.0^{2,9}.0^{4

Storage

Room temperature

Shipped In

Normal

Übersicht Specifications Namen und Kennungen Documentation Advanced Data Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Citations of This Product Lösungsrechner Bewertungen

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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Diosgenine is a steroid sapogenin used in the semi-synthesis of pregnenolone, cortisone, and progesterone. Diosgenin has estrogenic activity and can reduce the level of serum cholesterol.
A steroid sapogenin with estrogenic activity

Specifications

Synonyme

Spezifikationen & Reinheit

≥95%

Biochemische und physiologische Mechanismen

Steroidal saponin. Apopotic and antioxidant agent. Promotes angiogenesis in a HIF-1α dependent mechanism. Shows anticancer and immunosuppressive effects in vivo. Inhibits STAT3, PI3K, Akt, ERK and JNK phosphorylation and proinflammatory cytokine product

Storage

Room temperature

Verschickt in

Normal

Hinweis

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Reinheit

≥95%

Namen und Kennungen

Pubchem Sid

488187181

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488187181

Kanonisches Lächeln

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1

IUPAC Name

(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol

InChIKey

WQLVFSAGQJTQCK-VKROHFNGSA-N

INCHI

1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1

Isomere SMILES

C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O)C)C)C)OC1

WGK Deutschland

Molekulargewicht

414.62

Beilstein

94582

Reaxy-Rn

1296718

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1296718&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Klasse Prenol lipids
    - Subclass Triterpenoids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Klasse	Prenol lipids
Subclass	Triterpenoids
Intermediate Tree Nodes	Not available
Direct Parent	Triterpenoids
Alternative Parents	Spirostanes and derivatives 3-beta-hydroxysteroids 3-beta-hydroxy delta-5-steroids Delta-5-steroids Ketals Oxanes Tetrahydrofurans Secondary alcohols Cyclic alcohols and derivatives Oxacyclic compounds Hydrocarbon derivatives
Molecular Framework	Aliphatic heteropolycyclic compounds
Substituents	Triterpenoid - Spirostane skeleton - 3-hydroxy-delta-5-steroid - 3-hydroxysteroid - Hydroxysteroid - 3-beta-hydroxy-delta-5-steroid - 3-beta-hydroxysteroid - Steroid - Delta-5-steroid - Ketal - Oxane - Tetrahydrofuran - Cyclic alcohol - Secondary alcohol - Acetal - Organoheterocyclic compound - Oxacycle - Organic oxygen compound - Organooxygen compound - Alcohol - Hydrocarbon derivative - Aliphatic heteropolycyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as triterpenoids. These are terpene molecules containing six isoprene units.
External Descriptors	Spirostanols and derivatives
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

Zugehörige Ziele (menschlich)

STAT3 Tchem Signal transducer and activator of transcription 3 (3313 Activities)

Discover Target: STAT3

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

UGT1A4 Tbio UDP-glucuronosyltransferase 1A4 (288 Activities)

Discover Target: UGT1A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BXPC-3 (2997 Activities)

Lot Number	Certificate Type	Datum	Artikel
L2206637	Certificate of Analysis	Sep 01, 2026	D101265
L2206671	Certificate of Analysis	Sep 01, 2026	D101265
L2206678	Certificate of Analysis	Sep 01, 2026	D101265
L2206682	Certificate of Analysis	Sep 01, 2026	D101265
H2522791	Certificate of Analysis	Aug 23, 2025	D101265
H2512135	Certificate of Analysis	Aug 19, 2025	D101265
J1726060	Certificate of Analysis	May 12, 2025	D101265
G2114051	Certificate of Analysis	Apr 08, 2025	D101265
A2521008	Certificate of Analysis	Jul 11, 2024	D101265
A2521015	Certificate of Analysis	Jul 11, 2024	D101265
D1621022	Certificate of Analysis	Dec 14, 2023	D101265
C2330938	Certificate of Analysis	Sep 26, 2022	D101265
C2330939	Certificate of Analysis	Sep 26, 2022	D101265
C2330941	Certificate of Analysis	Sep 26, 2022	D101265
C2330942	Certificate of Analysis	Sep 26, 2022	D101265

Löslichkeit	Soluble in chloroform (50 mg/ml), ethanol (83 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), DMSO (<1 mg/ml at 25 °C), and methanol.,
Spezifische Drehung [α]	-126° (C=1,CHCl3)
Schmelzpunkt (°C)	205°C
Molekulargewicht	414.600 g/mol
XLogP3	5.700
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	414.313 Da
Monoisotopic Mass	414.313 Da
Topological Polar Surface Area	38.700 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	746.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	11
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Diosgenine - ≥95% , CAS No.512-04-9

Storage & shipping

Quality documents

Literature proof

Übersicht

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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📚 Citations by Application

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