Diosmin - 2mM in DMSO , CAS No.520-27-4

CAS: 520-27-4 Cat. No.: D408635 Molecular Weight: 608.54 EC Number: 208-289-7

GRADE & PURITY 2mM in DMSO

Synonyms

4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

Diosmin Diosmin is an agonist of the aryl hydrocarbon receptor (AhR) . Diosmin is a semisynthetic phlebotropic agent and a flavonoid found in a variety of citrus fruits.
In vitro

In vivo

Cell Data

cell lines：H441 cells

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Synonyms

4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-

Specifications & Purity

2mM in DMSO

Biochemical and Physiological Mechanisms

Diosmin is an agonist of the aryl hydrocarbon receptor (AhR). Diosmin is a semisynthetic phlebotropic agent and a flavonoid found in a variety of citrus fruits.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O
• WGK Germany: 3
• Molecular Weight: 608.54
• Reaxy-Rn: 1696798
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1696798&ln=

Chemical and Physical Properties

• Specific Rotation[α]: -121 ° (C=0.5, 0.1mol/L NaOH)
• Melt Point(°C): 283°C

References

1. Ruiyi Fan, Congyi Zhu, Diyang Qiu, Genlin Mao, Bernd Mueller-Roeber, Jiwu Zeng.  (2023)  Integrated transcriptomic and metabolomic analyses reveal key genes controlling flavonoid biosynthesis in Citrus grandis ‘Tomentosa’ fruits.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:36724705] [10.1016/j.plaphy.2023.01.050]

2. Chen Xian, Zhang Menghan, Zheng Lang, Deng Xiaoqin, Chen Qiang, Han Wendi, Huang Zhengjun, Weng Shaohuang.  (2024)  Effective Determination of Diosmin Using Nitrogen Doped Carbon Dots as Probe Based on Internal Filtering Effect.  JOURNAL OF FLUORESCENCE,      [PMID:39419896] [10.1007/s10895-024-03963-8]

3. Mengyao Wu, Xiaole Chen, Lei Zhang, Yingbin Shen, Tak-Ho Lo, Xinquan Yang.  (2025)  Multi-omics analysis reveals the anti-obesity and hepatoprotective properties in Termitomyces intermedius extracts.  Journal of Future Foods,      [PMID:] [10.1016/j.jfutfo.2024.11.022]

4. Jiayi Zhang, Jingzhi Wang, Junfeng Wang, Weifeng Ni, Shichao Liu, Daqing Zhao, Zhengqi Dong, Shiting Yu, Siming Wang, Weinan Wang, Meichen Liu.  (2025)  Integrated multi-omics and machine learning reveal the intrinsic relationship between color and flavor variations in processed ginseng products through major pigment dynamics and non-enzymatic pathways.  LWT-FOOD SCIENCE AND TECHNOLOGY,      [PMID:] [10.1016/j.lwt.2025.118161]

5. Yongmei Chen, Qingwen Wei, Jing Wang, Chuanyao Huang, Zhenghao Wang, Yuchun Liu.  (2025)  Studies on the Flavonoid Composition of Pleioblastus amarus Leaves and Shoots Based on Targeted Metabolomics.  Metabolites,  15  (11): (709).  [PMID:41295295] [10.3390/metabo15110709]

6. Dahe Qiao, Chun Yang, Xiaozeng Mi, Sihui Liang, Yan Guo, Juan Chen, Zhengwu Chen.  (2026)  Comprehensive evaluation of tea processing quality characteristics in ‘Qiancha 1′ tea plant cultivar: chemical profiling across tea types from multi-grade raw materials.  Applied Food Research,  6  (1): (101723).  [PMID:] [10.1016/j.afres.2026.101723]