Divarasib - Moligand™, ≥98% , Inhibitor of KRAS, CAS No.2417987-45-0, Inhibitor of KRAS

CAS: 2417987-45-0 Cat. No.: D609917 Summenformel: C₂₉H₃₂ClF₄N₇O₂ Molekulargewicht: 622.06 PubChem CID: 146624881

GRADE & PURITY Moligand™, ≥98%

Synonyms

2417917-17-8 | Divarasib [INN] | GDC 6036 [WHO-DD] | Divarasib | EX-A5694 | GLXC-25585 | (Z)-2-butenedioic acid; 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine | US11236068, Example 17a | E6S21PVT91 | RG6330 | RG-6330 | del

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Synonyme

2417917-17-8 | Divarasib [INN] | GDC 6036 [WHO-DD] | Divarasib | EX-A5694 | GLXC-25585 | (Z)-2-butenedioic acid; 2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine | US11236068, Example 17a | E6S21PVT91 | RG6330 | RG-6330 | del

Spezifikationen & Reinheit

Moligand™, ≥98%

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

INHIBITOR

Mechanismus der Wirkung

Inhibitor of KRAS

Reinheit

≥98%

Namen und Kennungen

• Kanonisches Lächeln: C[C@H]1CN(CCN1C2=NC(=NC3=C(C(=C(C=C32)Cl)C4=C(C(=CC(=N4)N)C)C(F)(F)F)F)OC[C@@H]5CCCN5C)C(=O)C=C
• Isomere SMILES: C[C@H]1CN(CCN1C2=NC(=NC3=C(C(=C(C=C32)Cl)C4=C(C(=CC(=N4)N)C)C(F)(F)F)F)OC[C@@H]5CCCN5C)C(=O)C=C
• PubChem CID: 146624881
• Molekulargewicht: 622.06

Zugehörige Ziele (menschlich)

KRAS Tclin GTPase KRas (0 Activities)

Discover Target: KRAS

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Molekulargewicht: 622.100 g/mol
• XLogP3: 5.400
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 6
• Exact Mass: 621.224 Da
• Monoisotopic Mass: 621.224 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 43
• Formal Charge: 0
• Complexity: 997.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1