DMPD 2HCl - AR, ≥96%, environmental protection reagent , CAS No.536-46-9

CAS: 536-46-9 Cat. No.: D110993 Molecular Weight: 209.12 Beilstein Registry Number: 3913463 EC Number: 208-635-7 PubChem CID: 2724166

GRADE & PURITY AR, ≥96%, environmental protection reagent

Synonyms

D0780 | N,N-Dimethyl-p-phenylenediaminedihydrochloride | N,N-Dimethyl-p-phenylenediamine dihydrochloride, suitable for peroxidase test, >=99.0% (titration) | N,N-Dimethyl-p-phenylenediammonium Dichloride | 4-Amino-N,N-dimethylaniline dihydrochloride | 4-d

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

A stain used in mircroscopy.

Specifications

Synonyms

D0780 | N, N-Dimethyl-p-phenylenediaminedihydrochloride | N, N-Dimethyl-p-phenylenediamine dihydrochloride, suitable for peroxidase test, >=99.0% (titration) | N, N-Dimethyl-p-phenylenediammonium Dichloride | 4-Amino-N, N-dimethylaniline dihydrochloride | 4-d

Specifications & Purity

AR, ≥96%, environmental protection reagent

Biochemical and Physiological Mechanisms

N, N-Dimethyl-p-phenylenediamine dihydrochloride is a stain used in mircroscopy.

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

AR

Purity

≥96%

Names and Identifiers

• Canonical Smiles: CN(C)C1=CC=C(C=C1)N.Cl.Cl
• IUPAC Name: 4-N,4-N-dimethylbenzene-1,4-diamine;dihydrochloride
• InChIKey: IAEDWDXMFDKWFU-UHFFFAOYSA-N
• INCHI: 1S/C8H12N2.2ClH/c1-10(2)8-5-3-7(9)4-6-8;;/h3-6H,9H2,1-2H3;2*1H
• Isomeric SMILES: CN(C)C1=CC=C(C=C1)N.Cl.Cl
• WGK Germany: 3
• RTECS: ST1300000
• PubChem CID: 2724166
• UN Number: 2811
• Packing Group: II
• Molecular Weight: 209.12
• Beilstein: 3913463

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic nitrogen compounds
    • Class Organonitrogen compounds
      • Subclass Amines
        • Level5 Tertiary amines
          • Level6 Tertiary alkylarylamines
            • Level7 Dialkylarylamines

• Kingdom: Organic compounds
• Superclass: Organic nitrogen compounds
• Class: Organonitrogen compounds
• Subclass: Amines
• Intermediate Tree Nodes: Tertiary amines - Tertiary alkylarylamines
• Direct Parent: Dialkylarylamines
• Alternative Parents: Aniline and substituted anilines Primary amines Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Aniline or substituted anilines - Dialkylarylamine - Benzenoid - Monocyclic benzene moiety - Organopnictogen compound - Hydrocarbon derivative - Hydrochloride - Primary amine - Aromatic homomonocyclic compound
• Description: This compound belongs to the class of organic compounds known as dialkylarylamines. These are aliphatic aromatic amines in which the amino group is linked to two aliphatic chains and one aromatic group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (2000 mg/ml at 20 °C), and alcohol.
• Sensitivity: Light & heat & air sensitive,Hygroscopic
• Melt Point(°C): 222°C
• Molecular Weight: 209.110 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 208.053 Da
• Monoisotopic Mass: 208.053 Da
• Topological Polar Surface Area: 29.300 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 93.400
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

1. Xinqiang Liang, Mekhrdod S. Kurboniyon, Yuanhan Zou, Kezong Luo, Shuhong Fang, Pengle Xia, Shufang Ning, Litu Zhang, Chen Wang.  (2023)  GSH-Triggered/Photothermal-Enhanced H2S Signaling Molecule Release for Gas Therapy.  Pharmaceutics,  15  (10): (2443).  [PMID:37896203] [10.3390/pharmaceutics15102443]

2. Yuzhi Qiu, Man Fan, Yiqian Wang, Xiuwen Hu, Jiawen Chen, Samir Kamel, Yajiang Yang, Xiangliang Yang, Hongfang Liu, Yanhong Zhu, Qin Wang.  (2023)  Sulfate-reducing bacteria loaded in hydrogel as a long-lasting H2S factory for tumor therapy.  JOURNAL OF CONTROLLED RELEASE,      [PMID:37406817] [10.1016/j.jconrel.2023.06.037]

3. Lu Jia, Yuzhu Wang, Tingting Hu, Chunyu Yang, Huiming Lin, Feng Zhang, Fengyu Qu, Liru Cui, Wei Guo.  (2023)  Boosting the tumor photothermal therapy with hollow CoSnSx-based injectable hydrogel via the sonodynamic and dual-gas therapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.143969]

4. Yang Bobo, Yin Changsheng, Zhang Yu, Xing Guangwei, Wang Suhua, Li Fang, Aschner Michael, Lu Rongzhu.  (2022)  Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, brain, and liver.  Toxicology Research,  11  (2): (374-384).  [PMID:35510234] [10.1093/toxres/tfac011]

5. Feng Zhu, Xingyun Hu, Linghao Kong, Xianjia Peng.  (2021)  Calcium sulfide-organosilicon complex for sustained release of H2S in strongly acidic wastewater: Synthesis, mechanism and efficiency.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:34364206] [10.1016/j.jhazmat.2021.126745]

6. Bobo Yang, Wenjun Zhao, Changsheng Yin, Yu Bai, Suhua Wang, Guangwei Xing, Fang Li, Jinsong Bian, Michael Aschner, Jiyang Cai, Haifeng Shi, Rongzhu Lu.  (2021)  Acute acrylonitrile exposure inhibits endogenous H2S biosynthesis in rat brain and liver: The role of CBS/3-MPST-H2S pathway in its astrocytic toxicity.  TOXICOLOGY,      [PMID:33486070] [10.1016/j.tox.2021.152685]

7. He Ding, Jianye Wei, Linyang Fang, Lili Feng, Shili Gai, Fei He, Linzhi Wu, Ziaur Rehman, Piaoping Yang.  (2024)  A Multichannel Metabolic Pathway Interference Strategy for Complete Energy Depletion-Mediated Cancer Therapy.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202312429]

8. Yinhong Xie, Mengchen Chi, Ruichen Dong, Sui Wu, Jinming Yang, Qin Wang, Junying Chen, Yajun Weng.  (2024)  A multi-target and responsive nanoplatform (MM/ZnS/ATV) combining H2S and atorvastatin for enhanced atherosclerosis therapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.153439]

9. Yanduo Yang, Chungeng Zhan, Yu Li, Jiajia Zeng, Keyue Lin, Jianliang Sun, Feng Jiang.  (2024)  In-situ reactivation and reuse of micronsized sulfidated zero-valent iron using SRB-enriched culture: A sustainable PRB technology.  WATER RESEARCH,      [PMID:38359598] [10.1016/j.watres.2024.121270]

10. Yi Zhang, Hao Guo, Gang Wang, Fang Lan, Shiyong Zhang.  (2025)  Poly-Lipoic Acid Trisulfide Particles: A New Donor With Continuous and Steady H2S Supply.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202511440]

11. Zhang Chunyu, Li An-Zhen, Yuan Bo-Jun, Liu Xiang, Liu Yuanbo, Kong Kejian, Shi Qiujin, Zhang Yixuan, Luo Yiqi, Li Shengnan, Zhou Hua, Duan Haohong.  (2025)  Electrochemical valorization of H2S in natural gas to sulfate under mild conditions.  Nature Communications,  16  (1): (1-15).  [PMID:40759988] [10.1038/s41467-025-62445-y]

12. Jun Zhao, Yangfeng Du, Wanqin Cai, Pei Zhang, Xiling Song, Wenxuan Ye, Yunping Peng, Jianfu Zhao, Siming Yu.  (2025)  pH and Glutathione-Responsive Sequentially Releasing Hydroxyl Radical and Hydrogen Sulfide Nanozyme for Effective Wound Infection Treatment via Bimodal Chemodynamic-Gas Therapy.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.5c03513]

13. Tianyou Wang, Zhou Shen, Qingxue Li, Di Wu, Xiaoping Yin, Yan Qin, Leyong Zeng.  (2025)  Bimetallic multi-enzyme nanozyme with spatiotemporal-regulated dual-gas release for enhancing catalytic/gas therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:] [10.1016/j.jcis.2025.139311]

14. Zhong Shao, Ke Li, Hao Guo, Yangyang Cheng, Shiyong Zhang.  (2025)  An oral H2S nanotherapeutics for hypertensive chronic kidney disease via synergistic antihypertensive and renoprotective activities.  JOURNAL OF CONTROLLED RELEASE,      [PMID:41260269] [10.1016/j.jconrel.2025.114419]