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DS-7423 - ≥99% , CAS No.1222104-37-1
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GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
🌎 Ship to: United States
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht
DS-7423 is a dual PI3K and mTOR inhibitor, with IC 50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR , respectively. DS-7423 possesses anti-tumor activity.
In Vitro
DS-7423 increases TP53 expression, the level of p-TP53 on Ser-46, and induced apoptosisrelated TP53 target genes (TP53AIP1 and PUMA) in OCCC cells. DS-7423 also inhibits other isoforms of class I PI3K (IC 50 values: PI3Kβ = 1,143 nM; PI3Kγ = 249 nM; PI3Kδ = 262 nM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
Specifications
Spezifikationen & Reinheit
≥99%
Biochemische und physiologische Mechanismen
DS-7423 is a dual PI3K and mTOR inhibitor, with IC 50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR , respectively. DS-7423 possesses anti-tumor activity.
Storage
Store at -20°C
Verschickt in
Ice chest + Ice pads
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Aktionsart
INHIBITOR
Reinheit
≥99%
Namen und Kennungen
| Molekulargewicht | 520.51 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemische und physikalische Eigenschaften
| Löslichkeit | DMSO : 100 mg/mL (192.12 mM; Need ultrasonic) |
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Lösungsrechner
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