DSPE PEG Azide, DSPE-PEG-N3 - MW 3400 Da

Cat. No.: D163601

GRADE & PURITY MW 3400 Da

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

1,2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated Polyethylene Glycol, DSPE PEG is a phospholipid PEG conjugate which has both hydrophilicity and hydrophobility. Pegylated phospholipids are excellent liposome formation materials that can be used for drug delivery, gene transfection and vaccine delivery as well. Nanocs azide PEG DSPE products can be used to prepare pegylated liposome using Click Chemistry. Azide reacts readily with alkyne or cycloocytne in aqueous solution with or without copper catalyst. Pegylation of phospholipids significantly improves the blood circulation time and stability for encapsulated drugs. These materials can also be used for targeted drug delivery by modifying their surfaces with targeting ligands such as antibodies, peptides.

Specifications

Specifications & Purity

MW 3400 Da

Storage

Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Chemical and Physical Properties

• Solubility: White/off-white solid or semi-solid depends on molecule weight;Soluble in warm aqeous solution as well as most organic solvents
• Sensitivity: Hygroscopic

References

1. Xu Zhao, Hanwei Huang, Mingyang Liu, Pengliang Wang, Shuhui Song, Zhenguo Cheng, Yang Yu, Fengming Liu, Yaohe Wang, Zhiqing Pang, Hongjun Li, Funan Liu.  (2025)  In vivo neutrophils hitchhiking for tumor targeting and microenvironment regulation boosts oncolytic virus therapy.  Cell Reports Medicine,      [PMID:40858105] [10.1016/j.xcrm.2025.102314]