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DUB-IN-1 - 10mM in DMSO , CAS No.924296-18-4
AVAILABLE TO ORDER
GRADE & PURITY 10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Why this grade
10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs) , with an IC 50 of 0.85 μM for USP8
In Vitro
DUBs-IN-1 (22 d) is an active inhibitor of ubiquitin-specific proteases, with an IC 50 of 0.85 μM for USP8. DUBs-IN-1 is inactive toward USP7 (IC 50 , >100 μM). DUBs-IN-1 and its analogs reduce the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC 50 s ranging from 0.5 μM to 1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:IC50: 0.24 μM (USP8)
Specifications
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
DUB-IN-1 is an active inhibitor of ubiquitin-specific proteases (USPs) , with an IC 50 of 0.85 μM for USP8.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
INHIBITOR
Names and Identifiers
| Molecular Weight | 337.33 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews
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