Duramycin - ≥90% , CAS No.1391-36-2

CAS: 1391-36-2 Cat. No.: D329629 Summenformel: C₈₉H₁₂₅N₂₃O₂₅S₃ Molekulargewicht: 2013.28 PubChem CID: 92043271

GRADE & PURITY ≥90%

Synonyms

27,46-(Methaniminopentaniminomethano)-6,43:15,40-bis(methanothiomethano)pyrrolo[2,1-d1][1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52]thiaheptadecaazacyclopentapentacontine, cyclic peptide deriv | Antibiotic PA 48009 | Lancovutide | Leucopeptin | Mol

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Übersicht

Duramycin is a polypeptide antibiotic with a defined 3-dimensional binding structure. Duramycin is the smallest known polypeptide, with only 19 amino acids. Duramycin enhances chloride secretion in airway epithelium. Duramycin is used in studies of cystic fibrosis and as a novel phosphatidylethanolamine-binding molecular probe. Duramycin is also known as Lancovutide, and Leucopeptin.

Specifications

Synonyme

27,46-(Methaniminopentaniminomethano)-6,43:15,40-bis(methanothiomethano)pyrrolo[2,1-d1][1,4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52]thiaheptadecaazacyclopentapentacontine, cyclic peptide deriv | Antibiotic PA 48009 | Lancovutide | Leucopeptin | Mol

Spezifikationen & Reinheit

≥90%

Storage

Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥90%

Namen und Kennungen

• Pubchem Sid: 504772728
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504772728
• Kanonisches Lächeln: CC1C2C(=O)NC(C(=O)NC(C(=O)NC3CSCC4C(=O)NC(CS1)C(=O)NC(CNCCCCC(NC(=O)C(CSCC(C(=O)NC(C(=O)NC(C(=O)N4)CCC(=O)N)CCCCN)N)NC(=O)C(NC(=O)CNC(=O)C(NC3=O)C(C(=O)O)O)CC(=O)N)C(=O)O)C(=O)NC(C(=O)NCC(=O)N5CCCC5C(=O)NC(C(=O)N2)CC6=CC=CC=C6)CC7=CC=CC=C7)C(C)C)CC8=CC=CC=C8
• IUPAC Name: (1S,4S,13S,16S,19S,22S,25S,28R,31S,37S,40S,44R,47S,50S,53S,56R,65S,70S)-44-amino-47-(4-aminobutyl)-37-(2-amino-2-oxoethyl)-50-(3-amino-3-oxopropyl)-4,16,22-tribenzyl-31-[(S)-carboxy(hydroxy)methyl]-70-methyl-2,5,8,14,17,20,23,26,29,32,35,38,45,48,51,54,57,67-octadecaoxo-25-propan-2-yl-42,69,72-trithia-3,6,9,15,18,21,24,27,30,33,36,39,46,49,52,55,58,60,66-nonadecazapentacyclo[38.18.9.319,56.328,53.09,13]triheptacontane-65-carboxylic acid
• InChIKey: BPIFGBWRBGTMHX-CREJVHTASA-N
• INCHI: 1S/C88H123N23O25S3/c1-44(2)67-85(131)107-60-42-138-41-59-80(126)106-61-43-139-45(3)68(86(132)102-55(76(122)108-67)34-48-22-11-6-12-23-48)109-77(123)54(33-47-20-9-5-10-21-47)101-83(129)62-26-17-31-111(62)66(115)38-95-72(118)53(32-46-18-7-4-8-19-46)100-78(124)57(103-81(61)127)36-93-30-16-14-25-52(87(133)134)99-79(125)58(105-75(121)56(35-64(92)113)96-65(114)37-94-84(130)69(110-82(60)128)70(116)88(135)136)40-137-39-49(90)71(117)97-50(24-13-15-29-89)73(119)98-51(74(120)104-59)27-28-63(91)112/h4-12,18-23,44-45,49-62,67-70,93,116H,13-17,24-43,89-90H2,1-3H3,(H2,91,112)(H2,92,113)(H,94,130)(H,95,118)(H,96,114)(H,97,117)(H,98,119)(H,99,125)(H,100,124)(H,101,129)(H,102,132)(H,103,127)(H,104,120)(H,105,121)(H,106,126)(H,107,131)(H,108,122)(H,109,123)(H,110,128)(H,133,134)(H,135,136)/t45-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58+,59+,60-,61-,62-,67-,68+,69-,70-/m0/s1
• Isomere SMILES: C[C@H]1[C@@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]3CSC[C@@H]4C(=O)N[C@@H](CS1)C(=O)N[C@@H](CNCCCC[C@H](NC(=O)[C@@H](CSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4)CCC(=O)N)CCCCN)N)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC3=O)[C@@H](C(=O)O)O)CC(=O)N)C(=O)O)C(=O)N[C@H](C(=O)NCC(=O)N5CCC[C@H]5C(=O)N[C@H](C(=O)N2)CC6=CC=CC=C6)CC7=CC=CC=C7)C(C)C)CC8=CC=CC=C8
• WGK Deutschland: 3
• RTECS: BV7100000
• PubChem CID: 92043271
• Molekulargewicht: 2013.28

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO (Slightly)