EGFR-IN-69 - 10mM in DMSO , CAS No.2433837-65-9

CAS: 2433837-65-9 Cat. No.: E654893 Summenformel: C₃₁H₃₇Cl₂N₇O₃S Molekulargewicht: 658.64

QUALITÄT & REINHEIT 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

EGFR-IN-69 (compound 17g) is a potent EGFR inhibitor, with IC 50 values of 4.3, 6.6 and 25.6 nM against EGFR L858R/T790M/C797S , EGFR L858R/T790M , and EGFR 19del/T790M/C797S , respectively. EGFR-IN-69 can be used for non-small-cell-lung-cancer (NSCLC) research

IC50& Target:EGFR L858R/T790M/C797S 4.3 ± 0.9 nM (IC 50 ) EGFR L858R/T790M 6.6 ± 0.8 nM (IC 50 ) EGFR del19 T790M C797S 25.6 ± 7.5 nM (IC 50 ) EGFR WT 816.0 ± 82 nM (IC 50 )

Spezifikationen

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

EGFR-IN-69 (compound 17g) is a potent EGFR inhibitor, with IC 50 values of 4.3, 6.6 and 25.6 nM against EGFR L858R/T790M/C797S , EGFR L858R/T790M , and EGFR 19del/T790M/C797S , respectively. EGFR-IN-69 can be used for non-small-cell-lung-cancer (NSCLC) re

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Namen und Kennungen

Molekulargewicht

658.64