Eltanexor Z-isomer - ≥96% , CAS No.1642300-78-4

CAS: 1642300-78-4 Cat. No.: E650555 Summenformel: C₁₇H₁₀F₆N₆O Molekulargewicht: 428.29 PubChem CID: 117763569

GRADE & PURITY ≥96%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.IC50：In Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC 50 s of 100 nM-50 μM, < 100 nM, > 30 μM, respectively.In Vivo:

Form:Solid

Specifications

Spezifikationen & Reinheit

≥96%

Biochemische und physiologische Mechanismen

Eltanexor Z-isomer (KPT-8602 Z-isomer) is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor.\nIC50：\nIn Vitro: Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC 50 s of 100 nM-50 μM, < 10

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Reinheit

≥96%

Namen und Kennungen

• Isomere SMILES: C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C2=NN(C=N2)/C=C(/C3=CN=CN=C3)\C(=O)N
• PubChem CID: 117763569
• Molekulargewicht: 428.29

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 50 mg/mL (116.74 mM; Need ultrasonic)
• Molekulargewicht: 428.290 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 4
• Exact Mass: 428.082 Da
• Monoisotopic Mass: 428.082 Da
• Topological Polar Surface Area: 99.600 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 626.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1