Determine the necessary mass, volume, or concentration for preparing a solution.
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224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
Moligand™, ≥96% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Protected from light Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Ergosterol peroxide, Ergosterol derivative, is a sterol found in edible or medicinal mushrooms. Ergosterol peroxide has anti-inflammatory, antitumor, and trypanocidal activity. Ergosterol peroxide suppresses LPS-induced phosphorylation of p38 MAPK, ERK MAPK, and JNK MAPK. Ergosterol peroxide suppresses LPS-induced DNA-binding activity of NF-κB p65 and C/EBPβ. Ergosterol peroxide suppresses LPS-induced TNF-α secretion and IL-1α/β expression. Ergosterol peroxide exerts cytostatic effects on cancer cells, increases intracellular ROS, induces CDKN1A expression, suppresses STAT1 expression, and induces apoptosis. Ergosterol peroxide disrupts Trypanosoma cruzi parasite membranes, shows trypanocidal activity. Ergosterol peroxide can be used for the research of leukemia, inflammatory responses and Chagas' disease
Specifications
Specifications & Purity
Moligand™, ≥96%
Storage
Store at 2-8°C, Protected from light
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Purity
≥96%
Names and Identifiers
| Canonical Smiles | CC(C)C(C)C=CC(C)C1CCC2C1(CCC3C24C=CC5(C3(CCC(C5)O)C)OO4)C |
|---|---|
| IUPAC Name | (1S,2R,5R,6R,9R,10R,13S,15S)-5-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-6,10-dimethyl-16,17-dioxapentacyclo[13.2.2.01,9.02,6.010,15]nonadec-18-en-13-ol |
| InChIKey | VXOZCESVZIRHCJ-KGHQQZOUSA-N |
| INCHI | 1S/C28H44O3/c1-18(2)19(3)7-8-20(4)22-9-10-23-25(22,5)13-12-24-26(6)14-11-21(29)17-27(26)15-16-28(23,24)31-30-27/h7-8,15-16,18-24,29H,9-14,17H2,1-6H3/b8-7+/t19-,20+,21-,22+,23+,24+,25+,26+,27+,28-/m0/s1 |
| Isomeric SMILES | C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@]24C=C[C@@]5([C@@]3(CC[C@@H](C5)O)C)OO4)C |
| Alternate CAS | 2061-64-5 |
| NSC Number | 31324 |
| MeSH Entry Terms | 3-hydroxy-5,7-epidioxyergosta-6,22-diene;5,8-epidioxyergosta-6,22-dien-3-ol;ergosterol endoperoxide;ergosterol peroxide;ergosterol-5,8-peroxide |
| Molecular Weight | 428.65 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Taxonomic Classification
Taxonomy Tree
- Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
- Class Steroids and steroid derivatives
- Subclass Ergostane steroids
- Class Steroids and steroid derivatives
- Superclass Lipids and lipid-like molecules
| Kingdom | Organic compounds |
|---|---|
| Superclass | Lipids and lipid-like molecules |
| Class | Steroids and steroid derivatives |
| Subclass | Ergostane steroids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Ergostane steroids |
| Alternative Parents | 1,2-dioxanes Secondary alcohols Dialkyl peroxides Cyclic alcohols and derivatives Oxacyclic compounds Hydrocarbon derivatives |
| Molecular Framework | Aliphatic heteropolycyclic compounds |
| Substituents | Ergostane-skeleton - Ortho-dioxane - Cyclic alcohol - Dialkyl peroxide - Secondary alcohol - Oxacycle - Organoheterocyclic compound - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Alcohol - Aliphatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as ergostane steroids. These are steroids with a structure based on the ergostane skeleton, which arises from the methylation of cholestane at the 24-position. |
| External Descriptors | 3beta-sterol - organic peroxide - ergostanoid - phytosterols |
3D Structure
Interactive Chemical Structure Model
Associated Targets(Human)
AKR1B1 Tclin Aldose reductase (1404 Activities)
NR1H4 Tclin Bile acid receptor FXR (6228 Activities)
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MCF7 (126967 Activities)
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SNU1 (253 Activities)
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SNU-354 (13 Activities)
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A549 (127892 Activities)
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HepG2 (196354 Activities)
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HUVEC (11049 Activities)
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KB (17409 Activities)
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MDA-MB-231 (73002 Activities)
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Associated Targets(non-human)
Nos2 Nitric oxide synthase, inducible (3573 Activities)
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Pseudomonas aeruginosa (123386 Activities)
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Staphylococcus aureus (210822 Activities)
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Escherichia coli (133304 Activities)
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Mycobacterium tuberculosis (203094 Activities)
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Candida (1648 Activities)
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Leishmania amazonensis (3813 Activities)
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Trypanosoma cruzi (99888 Activities)
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Hepatitis B virus (7925 Activities)
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B16 (5829 Activities)
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PC-12 (7051 Activities)
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RAW264.7 (28094 Activities)
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Vero (26788 Activities)
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BV-2 (3710 Activities)
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Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
| Sensitivity | Light sensitive；Moisture sensitive. |
|---|---|
| Molecular Weight | 428.600 g/mol |
| XLogP3 | 6.700 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 4 |
| Exact Mass | 428.329 Da |
| Monoisotopic Mass | 428.329 Da |
| Topological Polar Surface Area | 38.700 Ų |
| Heavy Atom Count | 31 |
| Formal Charge | 0 |
| Complexity | 772.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 10 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
Solution Calculators
Reviews
Customer Reviews
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