Ertapenem sodium(L-749345) - GR, Moligand™ , Bacterial penicillin-binding protein inhibitor, CAS No.153773-82-1, Bacterial penicillin-binding protein inhibitor

CAS: 153773-82-1 Cat. No.: E302984 Summenformel: C₂₂H₂₄N₃NaO₇S Molekulargewicht: 497.5 EG-Nummer: 836-232-1

QUALITÄT & REINHEIT Moligand™, GR

Synonyms

Ertapenem sodium | Q-201065 | MK-0826 | L-749345;MK-826 | AC-1633 | Ertapenem sodium salt | Sodium (4R,5S,6S)-3-(((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Übersicht

Application

Ertapenem Monosodium is a β-lactam antibiotics with broad-spectrum potency and high β-lactamase resistance.

Spezifikationen

Synonyme

Ertapenem sodium | Q-201065 | MK-0826 | L-749345;MK-826 | AC-1633 | Ertapenem sodium salt | Sodium (4R,5S,6S)-3-(((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

Spezifikationen & Reinheit

GR, Moligand™

Biochemische und physiologische Mechanismen

Ertapenem sodium is a broad spectrum and long acting β-lactam antibiotic. Ertapenem sodium has a broad-spectrum anti-anaerobic activity against a variety of anaerobes with a mode MIC of 0.12 μg/mL. Ertapenem sodium can be used for the research of severe i

Storage

Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

GR, Moligand™

Aktionsart

INHIBITOR

Mechanismus der Wirkung

Bacterial penicillin-binding protein inhibitor

Namen und Kennungen

Pubchem Sid

528770363

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528770363

Kanonisches Lächeln

CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)NC4=CC=CC(=C4)C(=O)O)C(=O)[O-])C(C)O.[Na+]

IUPAC Name

sodium;(4R,5S,6S)-3-[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

InChIKey

ZXNAQFZBWUNWJM-HRXMHBOMSA-M

INCHI

1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1

Isomere SMILES

C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)NC4=CC=CC(=C4)C(=O)O)C(=O)[O-])[C@@H](C)O.[Na+]

Alternative CAS-Nummer

153832-46-3

Molekulargewicht

497.5

Reaxy-Rn

43455531

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=43455531&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Lactams
      • Subclass Beta lactams
        • Ebene5 Carbapenems
          • Ebene6 Thienamycins

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Lactams
• Subclass: Beta lactams
• Intermediate Tree Nodes: Carbapenems
• Direct Parent: Thienamycins
• Alternative Parents: Alpha amino acids and derivatives Benzoic acids Benzoyl derivatives Pyrroline carboxylic acids Azepines Vinylogous thioesters Dicarboxylic acids and derivatives Tertiary carboxylic acid amides Pyrrolidines Amino acids Secondary alcohols Azetidines Thioenol ethers Dialkylamines Carboxylic acids Carboximidic acids Sulfenyl compounds Azacyclic compounds Propargyl-type 1,3-dipolar organic compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Thienamycin - Alpha-amino acid or derivatives - Benzoic acid or derivatives - Benzoic acid - Pyrroline carboxylic acid or derivatives - Pyrroline carboxylic acid - Benzoyl - Azepine - Benzenoid - Dicarboxylic acid or derivatives - Monocyclic benzene moiety - Vinylogous thioester - Pyrrolidine - Pyrroline - Tertiary carboxylic acid amide - Secondary alcohol - Amino acid - Azetidine - Amino acid or derivatives - Carboxamide group - Thioenolether - Azacycle - Organic alkali metal salt - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid derivative - Carboxylic acid - Secondary aliphatic amine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Sulfenyl compound - Secondary amine - Organic salt - Organic oxygen compound - Amine - Carbonyl group - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Alcohol - Organic zwitterion - Organic nitrogen compound - Organic sodium salt - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as thienamycins. These are beta-lactam antibiotics that differ from penicillins in having the thiazolidine sulfur atom replaced by carbon, the sulfur then becoming the first atom in the side chain.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Hygroscopic;Moisture sensitive
• Schmelzpunkt (°C): >174ºC