Ethephon - ≥90%(HPLC) , CAS No.16672-87-0

CAS: 16672-87-0 Cat. No.: E113521 Molecular Weight: 144.49 Beilstein Registry Number: 1751208 EC Number: 240-718-3

GRADE & PURITY ≥90%(HPLC)

Synonyms

Chloroethyl)phosphonic acid | Ethephon [ANSI] | PREP | ETHEPHON [HSDB] | Terpal | Ethel | NCGC00163720-03 | NCGC00163720-05 | 2-(Chloroethyl) Phosphonic Acid-d4 | Ethephon, PESTANAL(R), analytical standard | Ethrel-R (Salt/Mix) | Kamposan | Ethrel-E | Aci

Storage

Store at 2-8°C

Shipped In

Wet ice

Specifications

Synonyms

Chloroethyl)phosphonic acid | Ethephon [ANSI] | PREP | ETHEPHON [HSDB] | Terpal | Ethel | NCGC00163720-03 | NCGC00163720-05 | 2-(Chloroethyl) Phosphonic Acid-d4 | Ethephon, PESTANAL(R), analytical standard | Ethrel-R (Salt/Mix) | Kamposan | Ethrel-E | Aci

Specifications & Purity

≥90%(HPLC)

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥90%(HPLC)

Names and Identifiers

• Canonical Smiles: C(CCl)P(=O)(O)O
• IUPAC Name: 2-chloroethylphosphonic acid
• InChIKey: UDPGUMQDCGORJQ-UHFFFAOYSA-N
• INCHI: 1S/C2H6ClO3P/c3-1-2-7(4,5)6/h1-2H2,(H2,4,5,6)
• Isomeric SMILES: C(CCl)P(=O)(O)O
• WGK Germany: 2
• RTECS: SZ7100000
• UN Number: 2588
• Molecular Weight: 144.49
• Beilstein: 1751208
• Reaxy-Rn: 1751208
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1751208&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Organic phosphonic acids and derivatives
      • Subclass Organic phosphonic acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Organic phosphonic acids and derivatives
• Subclass: Organic phosphonic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic phosphonic acids
• Alternative Parents: Organopnictogen compounds Organophosphorus compounds Organochlorides Organic oxides Hydrocarbon derivatives Alkyl chlorides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organophosphonic acid - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organophosphorus compound - Organochloride - Organohalogen compound - Alkyl halide - Alkyl chloride - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as organic phosphonic acids. These are organic compounds containing phosphonic acid.
• External Descriptors: Pesticides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Oryza sativa (2923 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Vitis vinifera (99 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Easily soluble in water, methanol, acetone, ethylene glycol, propylene glycol, slightly soluble in toluene, insoluble in petroleum ether.
• Sensitivity: Moisture sensitive.
• Melt Point(°C): 70-72°C
• Molecular Weight: 144.490 g/mol
• XLogP3: -1.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 143.974 Da
• Monoisotopic Mass: 143.974 Da
• Topological Polar Surface Area: 57.500 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 86.900
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Renchi Chen, Yingyin Wu, Xiaobo Wei, Zhihai Huang, Linchun Mao.  (2023)  Ethylene promotes ABA biosynthesis by repressing the expression of miR161 in postharvest strawberry fruit.  POSTHARVEST BIOLOGY AND TECHNOLOGY,      [PMID:] [10.1016/j.postharvbio.2023.112302]

2. Hui Zhao, Xiangyu Liu, Yulong Sun, Juan Liu, Michael Gatheru Waigi.  (2023)  Effects and mechanisms of plant growth regulators on horizontal transfer of antibiotic resistance genes through plasmid-mediated conjugation.  CHEMOSPHERE,      [PMID:36720410] [10.1016/j.chemosphere.2023.137997]

3. Shuhuai Li, Chaohai Pang, Xionghui Ma, Haibo Li, Min Zhao, Chunhua Liu, Jinhui Luo.  (2020)  A gold nanoparticle-loaded molecularly imprinted switch sensor with high sensitivity to ethephon.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2020.105025]

4. Jia Honglei, Chen Sisi, Liu Dan, Liesche Johannes, Shi Cong, Wang Juan, Ren Meijuan, Wang Xiaofeng, Yang Jun, Shi Wei, Li Jisheng.  (2018)  Ethylene-Induced Hydrogen Sulfide Negatively Regulates Ethylene Biosynthesis by Persulfidation of ACO in Tomato Under Osmotic Stress.  Frontiers in Plant Science,      [PMID:30386366] [10.3389/fpls.2018.01517]

5. Wei-bing YANG, Yong LI, Yan-ping YIN, Wen-wen JIANG, Dian-liang PENG, Zheng-yong CUI, Dong-qing YANG, Zhen-lin WANG.  (2014)  Ethylene and Spermidine in Wheat Grains in Relation to Starch Content and Granule Size Distribution Under Water Deficit.  Journal of Integrative Agriculture,      [PMID:] [10.1016/S2095-3119(13)60726-1]

6. Qianqian Liu, Rongrong Huang, Jiaqi Tang, Helan Zhang, Mei Liu, Yu Fang.  (2024)  A Nanofilm-Based Fluorescent Sensor toward Highly Efficient Detection of Ethephon.  ANALYTICAL CHEMISTRY,      [PMID:38302113] [10.1021/acs.analchem.3c04999]

7. Cai Zeping, Dai Yinuo, Jin Xia, Xu Hui, Huang Zhen, Xie Zhenyu, Yu Xudong, Luo Jiajia.  (2024)  Ambient temperature regulates root circumnutation in rice through the ethylene pathway: transcriptome analysis reveals key genes involved.  Frontiers in Plant Science,      [PMID:38525142] [10.3389/fpls.2024.1348295]

8. Liu Yitong, Liu Shuangrong, Jing Yanjun, Li Jialong, Lin Rongcheng.  (2025)  Light regulates seed dormancy through FHY3-mediated activation of ACC OXIDASE 1 in Arabidopsis.  PLANT MOLECULAR BIOLOGY,  115  (2): (1-13).  [PMID:40082285] [10.1007/s11103-025-01559-9]

9. Renchi Chen, Yuhua Yan, Weiliang Guan, Zhihai Huang.  (2025)  Stimulation of Abscisic Acid Biosynthesis by Ethylene with Suppressive Action of MiR396 in Postharvest Strawberry Fruits.  Horticulturae,  11  (11): (1280).  [PMID:] [10.3390/horticulturae11111280]

10. Jialiang Liu, Tongtong Liang, Yue Xiang, Benfeng Zhang, Lisha Zhu, Xiangbin Xu, Xuequn Shi, Zhengke Zhang.  (2026)  AP2/ERF Transcription Factor MiRAP2.11 Mediates Ethylene-Induced Starch Degradation in Postharvest Mango Fruit.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:] [10.1021/acs.jafc.5c16097]