Etomoxir - Moligand™, ≥98% , CAS No.124083-20-1

CAS: 124083-20-1 Cat. No.: E124862 Summenformel: C17H23ClO4 Molekulargewicht: 326.82
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
ETOMOXIR [WHO-DD] | HY-50202 | STK709190 | DTXSID801025772 | Etomoxir [INN] | AC-32627 | (R)-(+)-Etomoxir | 2-OXIRANECARBOXYLIC ACID, 2-(6-(4-CHLOROPHENOXY)HEXYL)-, ETHYL ESTER, (2R)- | CHEBI:95011 | NCGC00378789-04 | BDBM50237625 | UNII-MSB3DD2XP6 | GTPL
Storage
Vor Licht geschützt,Lagerung bei -20°C,Argon geladen
Shipped In
Eistruhe + Eispads
★
Size
Deutschland (EU)
USA*
Price
Qty
5mg
E124862-5mg
—
3 Auf Lager
33,76€
10mg
E124862-10mg
—
3 Auf Lager
60,65€
25mg
E124862-25mg
—
2 Auf Lager
128,34€
50mg
E124862-50mg
—
3 Auf Lager
205,57€
100mg
E124862-100mg
—
1 Auf Lager
348,74€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Vor Licht geschützt,Lagerung bei -20°C,Argon geladen Ships Eistruhe + Eispads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Etomoxir ist ein zellpermeabler, irreversibler und stereospezifischer Inhibitor der Carnitin-Palmitoyltransferase (CPT)-1- und DGAT-Aktivität in den Mitochondrien von H9c2-Myoblastenzellen des Rattenherzens in einer Konzentration von 1-80 μM bzw. 40 μM.

Specifications

Synonyme
ETOMOXIR [WHO-DD] | HY-50202 | STK709190 | DTXSID801025772 | Etomoxir [INN] | AC-32627 | (R)-(+)-Etomoxir | 2-OXIRANECARBOXYLIC ACID, 2-(6-(4-CHLOROPHENOXY)HEXYL)-, ETHYL ESTER, (2R)- | CHEBI:95011 | NCGC00378789-04 | BDBM50237625 | UNII-MSB3DD2XP6 | GTPL
Spezifikationen & Reinheit
Moligand™, ≥98%
Biochemische und physiologische Mechanismen
Ein Hemmstoff der Carnitin-Palmitoyltransferase A (CPT1), die für die Oxidation langkettiger Acyl-CoA-Ester erforderlich ist. Auch ein starker Inhibitor der mitochondrialen CPT1 und ein Kandidat als Antidiabetikum.CPT1-Inhibitor. Hemmt die β-Oxidation in
Storage
Vor Licht geschützt,Lagerung bei -20°C,Argon geladen
Verschickt in
Eistruhe + Eispads
Note
Moligand™
Hinweis
Wenn möglich, sollten Sie die Lösungen noch am selben Tag zubereiten und verwenden. Wenn Sie jedoch Stammlösungen im Voraus herstellen müssen, empfehlen wir Ihnen, die Lösung als Aliquote in dicht verschlossenen Fläschchen bei -20°C zu lagern. Diese sind in der Regel bis zu einem Monat haltbar. Vor der Verwendung und vor dem Öffnen des Fläschchens empfehlen wir, das Produkt mindestens 1 Stunde lang auf Raumtemperatur kommen zu lassen. Toxisch, siehe SDS für weitere Informationen. Benötigen Sie weitere Ratschläge zur Löslichkeit, Verwendung und Handhabung? Bitte besuchen Sie unsere Seite mit den häufig gestellten Fragen (FAQ) für weitere Informationen.
Reinheit
≥98%
Namen und Kennungen
Pubchem Sid504764958
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504764958
Kanonisches LächelnCCOC(=O)C1(CO1)CCCCCCOC2=CC=C(C=C2)Cl
IUPAC Nameethyl (2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate
InChIKeyDZLOHEOHWICNIL-QGZVFWFLSA-N
INCHI1S/C17H23ClO4/c1-2-20-16(19)17(13-22-17)11-5-3-4-6-12-21-15-9-7-14(18)8-10-15/h7-10H,2-6,11-13H2,1H3/t17-/m1/s1
Isomere SMILES CCOC(=O)[C@]1(CO1)CCCCCCOC2=CC=C(C=C2)Cl
Molekulargewicht 326.82
Reaxy-Rn 8273691
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8273691&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
KlassePhenol ethers
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPhenol ethers
Alternative Parents Phenoxy compounds  Fatty acid esters  Chlorobenzenes  Alkyl aryl ethers  Oxirane carboxylic acids  Aryl chlorides  Carboxylic acid esters  Oxacyclic compounds  Monocarboxylic acids and derivatives  Dialkyl ethers  Organochlorides  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Phenoxy compound - Phenol ether - Alkyl aryl ether - Chlorobenzene - Fatty acid ester - Halobenzene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Fatty acyl - Oxirane carboxylic acid or derivatives - Oxirane carboxylic acid - Carboxylic acid ester - Oxacycle - Carboxylic acid derivative - Organoheterocyclic compound - Dialkyl ether - Oxirane - Ether - Monocarboxylic acid or derivatives - Organic oxide - Organooxygen compound - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organochloride - Organohalogen compound - Aromatic heteromonocyclic compound
BeschreibungThis compound belongs to the class of organic compounds known as phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring.
External Descriptors Not available
3D-Struktur
Interaktives chemisches Strukturmodell





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Wirkungsmechanismen
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

30 results found

Lot NumberCertificate TypeDatumArtikel
K2407512Certificate of AnalysisAug 03, 2026 E124862
K2407508Certificate of AnalysisAug 03, 2026 E124862
G2609497Certificate of AnalysisJun 26, 2026 E124862
G2609480Certificate of AnalysisJun 26, 2026 E124862
G2609470Certificate of AnalysisJun 26, 2026 E124862
G2609468Certificate of AnalysisJun 26, 2026 E124862
E2420218Certificate of AnalysisMar 11, 2026 E124862
E2420220Certificate of AnalysisMar 11, 2026 E124862
E2420221Certificate of AnalysisMar 11, 2026 E124862
G2226517Certificate of AnalysisFeb 04, 2026 E124862
L2525402Certificate of AnalysisDec 11, 2025 E124862
L2525401Certificate of AnalysisDec 11, 2025 E124862
L2525400Certificate of AnalysisDec 11, 2025 E124862
L2525399Certificate of AnalysisDec 11, 2025 E124862
L2525391Certificate of AnalysisDec 11, 2025 E124862
B1526025Certificate of AnalysisJun 17, 2025 E124862
F2505356Certificate of AnalysisMay 19, 2025 E124862
F2505355Certificate of AnalysisMay 19, 2025 E124862
F2505354Certificate of AnalysisMay 19, 2025 E124862
K2407509Certificate of AnalysisOct 17, 2024 E124862
K2407510Certificate of AnalysisOct 17, 2024 E124862
K2407511Certificate of AnalysisOct 17, 2024 E124862
K2407513Certificate of AnalysisOct 17, 2024 E124862
D2525012Certificate of AnalysisOct 17, 2024 E124862
E2420222Certificate of AnalysisMay 10, 2024 E124862
E2420219Certificate of AnalysisMay 10, 2024 E124862
E2420216Certificate of AnalysisMay 10, 2024 E124862
G2227021Certificate of AnalysisJun 11, 2022 E124862
G2226522Certificate of AnalysisJun 11, 2022 E124862
G2226515Certificate of AnalysisJun 11, 2022 E124862

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Chemische und physikalische Eigenschaften
LöslichkeitSoluble in Chloroform, Ethyl Acetate
EmpfindlichkeitLight sensitive
Molekulargewicht326.800 g/mol
XLogP34.300
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count11
Exact Mass326.128 Da
Monoisotopic Mass326.128 Da
Topological Polar Surface Area48.100 Ų
Heavy Atom Count22
Formal Charge0
Complexity342.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
FAQs und Artikel
Citations of This Product
Referenzen
1. Cui Tang, Hui Wang, Lina Guo, Chan Zou, Jianming Hu, Hanyong Zhang, Wenhu Zhou, Guoping Yang.  (2023)  CpG-Conjugated Silver Nanoparticles as a Multifunctional Nanomedicine to Promote Macrophage Efferocytosis and Repolarization for Atherosclerosis Therapy.  ACS Applied Materials & Interfaces,      [PMID:37910772] [10.1021/acsami.3c11227]
2. Lingxiang Ran, Qiu Chen, Xingyu Lu, Zhixiang Gao, Fengmei Cui, Xiaolong Liu, Boxin Xue.  (2023)  Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:37224756] [10.1016/j.biopha.2023.114903]
3. Jin Nan, Bi Aiwei, Lan Xiaojing, Xu Jun, Wang Xiaomin, Liu Yingluo, Wang Ting, Tang Shuai, Zeng Hanlin, Chen Ziqi, Tan Minjia, Ai Jing, Xie Hua, Zhang Tao, Liu Dandan, Huang Ruimin, Song Yue, Leung Elaine Lai-Han, Yao Xiaojun, Ding Jian, Geng Meiyu, Lin Shu-Hai, Huang Min.  (2019)  Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.  Nature Communications,  10  (1): (1-15).  [PMID:31221965] [10.1038/s41467-019-10427-2]
4. Jiao Shihong, Tang Binghua, Wang Yong, Li Chun, Zeng Zifan, Cui Lixia, Zhang Xuefeng, Shao Mingyan, Guo Dongqing, Wang Qiyan.  (2018)  Pro-angiogenic Role of Danqi Pill Through Activating Fatty Acids Oxidation Pathway Against Coronary Artery Disease.  Frontiers in Pharmacology,      [PMID:30564122] [10.3389/fphar.2018.01414]
5. Jing Wang, Nuli Xie, Shan Lu, Bo Xiao, Yangqin Ou, Qingnian Li, Dexian Liu, Wenhu Zhou.  (2024)  CpG and Rutin Co-Loaded DNA Tetrahedra for Targeted Therapy of Intracerebral Hemorrhage: Synergistic Hematoma Clearance and Neuroinflammation Inhibition.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202403469]
6. Xiangying Zou, Jiayu Jia, Tengfei Zhu, Shouping Cai, Yiman He, Shunde Su, Yu Fang, Jian Li, Guifang Lin, Jun Su.  (2024)  Identification of pine wood nematode (Bursaphelenchus xylophilus) loading response genes in Japanese pine sawyer (Monochamus alternatus) through comparative genomics and transcriptomics.  PEST MANAGEMENT SCIENCE,      [PMID:38511764] [10.1002/ps.8090]
7. Zhonghua Dong, Xiao Li, Xuan Wang, Jingya Xu, Wei Xu.  (2025)  Ergosterol from Edible Fungi: Enhancing Fatty Acid Oxidation via CPT1A to Protect Against Diabetic Kidney Disease.  Food & Function,      [PMID:40704985] [10.1039/D5FO00371G]
8. Kefan Zheng, Hongdi Cui, Ziheng Tang, Entong Song, Qingran Kong, Jiaming Zhang, Hao Li, Qi Zhao.  (2025)  Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice.  Frontiers in Cell and Developmental Biology,      [PMID:41415208] [10.3389/fcell.2025.1683028]
9. Li Yuan, Han Dongyang, Liu Junjie, Qiao Yuxin, Wei Jiaoxia, Lu Haitao, Yao Li.  (2026)  A novel role for decadienyl-L-carnitine in pulmonary vascular remodeling and the underlying interventional mechanism of osthole.  Chinese Medicine,  21  (1): (87).  [PMID:41840734] [10.1186/s13020-026-01362-8]
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