Recombinant Human KRBA1 Protein: Key Facts & FAQs

Recombinant Human KRBA1 Protein is a research-grade recombinant protein derived from the human KRBA1 gene, offered by Aladdin Scientific to support studies involving KRAB domain-containing zinc finger protein biology and related cellular regulatory mechanisms.

Product Name

Recombinant Human KRBA1 Protein

SKU

rp375414

Source

Human (Homo sapiens) KRBA1 gene

Protein Family

KRAB domain-containing zinc finger protein family

Supplier

Aladdin Scientific

Intended Use

Research use only (RUO); not for diagnostic or therapeutic use

What Is KRBA1 and Why Is It Relevant to Research?

KRBA1 (KRAB-A domain-containing protein 1) is a human protein encoded by the KRBA1 gene. It belongs to the superfamily of KRAB domain-containing zinc finger proteins (KRAB-ZFPs), which constitute one of the largest families of transcriptional regulators in mammals. Members of this family typically function as transcriptional repressors and are implicated in a wide range of cellular processes including gene silencing, differentiation, and genome stability.

Recombinant Human KRBA1 Protein enables researchers to study the biochemical properties, binding partners, and regulatory functions of KRBA1 in vitro without the variability inherent to cell-based expression systems. It is a valuable tool for proteomics, interaction studies, and functional assays.

Product Specifications and Quality

Recombinant Human KRBA1 Protein (SKU: rp375414) is produced using recombinant expression technology to ensure batch-to-batch consistency and high purity suitable for demanding research applications. Researchers should consult the product datasheet for detailed specifications including:

• Expression system: Please refer to the official product datasheet for confirmed expression host details.
• Purity: Determined by SDS-PAGE and/or other analytical methods; specific purity values are stated on the datasheet.
• Formulation and buffer: Refer to the datasheet for exact formulation details.
• Molecular weight: Confirm predicted and apparent molecular weight values on the product datasheet.

All Aladdin Scientific recombinant proteins are manufactured under strict quality control conditions. For the most current and authoritative specifications, always refer to the lot-specific Certificate of Analysis (CoA) available upon request.

Recommended Applications and Handling

Recombinant Human KRBA1 Protein is intended for research use only and may be applicable in the following experimental contexts:

• In vitro binding assays: Investigating protein–protein interactions involving KRBA1.
• Western blot controls: As a positive control for detection of KRBA1 in cell or tissue lysates.
• ELISA standards: As a reference standard in sandwich or indirect ELISA formats.
• Functional studies: Exploring transcriptional repression or other regulatory activities attributed to KRAB domain proteins.

Always centrifuge the vial briefly before opening. Avoid repeated freeze-thaw cycles, which can compromise protein integrity and activity. Aliquot the protein into single-use volumes upon first thaw to maximize stability. Store according to the conditions specified on the product datasheet and CoA.

Ordering, Storage, and Technical Support

Ordering: Recombinant Human KRBA1 Protein is available from Aladdin Scientific under SKU rp375414. To place an order, visit the Aladdin Scientific website, contact your local distributor, or reach out to our customer service team. Bulk quantities and custom formulations may be available upon request.

Storage: Store the protein according to the conditions indicated on the product label and datasheet. As a general best practice for recombinant proteins, avoid exposure to repeated freeze-thaw cycles and store at the recommended temperature (typically –20 °C or –80 °C for long-term storage; confirm with the datasheet).

Technical Support: For application-specific guidance, troubleshooting, or additional technical documentation including SDS, CoA, or datasheet, please contact Aladdin Scientific technical support. Our team is available to assist with protocol optimization and product selection.

Frequently asked questions

What is Recombinant Human KRBA1 Protein used for in research?

Recombinant Human KRBA1 Protein is used to study the biochemical and functional properties of the KRBA1 protein, a KRAB domain-containing zinc finger protein involved in transcriptional regulation. Typical applications include in vitro protein interaction assays, Western blot positive controls, ELISA reference standards, and functional studies of KRAB-domain-mediated transcriptional repression.

How should Recombinant Human KRBA1 Protein be stored to maintain stability?

To maintain protein stability and activity, store Recombinant Human KRBA1 Protein according to the conditions specified on the product datasheet and Certificate of Analysis. As a general guideline, avoid repeated freeze-thaw cycles by aliquoting the protein into single-use volumes upon first thaw, and store long-term at –20 °C or –80 °C as recommended.

How do I order Recombinant Human KRBA1 Protein from Aladdin Scientific?

You can order Recombinant Human KRBA1 Protein (SKU: rp375414) directly through the Aladdin Scientific website, by contacting your local authorized distributor, or by reaching out to the Aladdin Scientific customer service team. For bulk orders or custom formulations, please contact us in advance to discuss your requirements.

Is Recombinant Human KRBA1 Protein suitable for diagnostic or therapeutic applications?

No. Recombinant Human KRBA1 Protein (rp375414) is designated for research use only (RUO) and is not approved or validated for use in diagnostic, therapeutic, or clinical procedures. Researchers must comply with all applicable institutional and regulatory requirements when using this product.

Where can I find the datasheet and Certificate of Analysis for rp375414?

The product datasheet for Recombinant Human KRBA1 Protein (rp375414) is available on the Aladdin Scientific product page. The lot-specific Certificate of Analysis (CoA) can be requested by contacting Aladdin Scientific customer service or technical support, providing your lot number for accurate documentation.

References

1. Aladdin Scientific product page: Recombinant Human KRBA1 Protein, SKU rp375414.
2. Urrutia R. KRAB-containing zinc-finger repressor proteins. Genome Biology, 2003.

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.