Azaindoles

Azaindoles are fused heteroarenes. A heteroarene (hetarene) can be understood as an aromatic ring system in which one or more carbon atoms (or carbon fragments) are replaced by heteroatoms such as N, O, or S, while aromaticity is retained.

Azaindoles and their derivatives have shown remarkable biological activity and have therefore received considerable attention in drug optimization strategies. The four azaindole positional isomers link together the pyridine and pyrrole rings by a fused C-C bond while having all the criteria ...