1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Renal function biomarker research is used to evaluate renal status from multiple dimensions, including glomerular filtration, tubular injury, filtration barrier integrity, and renal endocrine regulation. Traditional indicators such as serum creatinine, blood urea nitrogen, and urinary protein ...
Plasmid extraction methods should be selected according to downstream experimental purpose, plasmid copy number, plasmid size, preparation scale, and quality control requirements. Clone verification, sequencing, restriction digestion, cell transfection, viral packaging, and large plasmid ...
Tag antibodies are used to recognize exogenous tag sequences in recombinant proteins and are commonly used detection tools in expression validation, protein localization, immunoprecipitation, interaction analysis, and purification process monitoring. Tags such as His, Flag, HA, Myc, V5, GST, ...
Detection of hepatobiliary metabolism-related indicators is used to evaluate hepatocyte synthesis and transport, bile formation, biliary excretion, cholestasis, cholesterol homeostasis, and bile discharge function from the perspectives of bile acids, bilirubin, cholesterol, cholesterol esters, ...
Animal models of acute lung injury are used to simulate alveolar epithelial and pulmonary vascular endothelial injury, inflammatory cell infiltration, disruption of the alveolar-capillary barrier, pulmonary edema, and hypoxemic respiratory dysfunction. They are important experimental systems for ...
CRISPR/Cas9 is currently one of the most widely used targeted gene editing technologies. It can generate DNA breaks at specific sites through RNA-guided Cas9 nuclease activity and achieve gene knockout, targeted knock-in, point mutation construction, and functional screening by using the ...
Animal models of acute liver injury are used to simulate hepatocellular necrosis, inflammatory responses, oxidative stress, cholestasis, or metabolic disorders occurring within a short period of time. They are important experimental systems for studying mechanisms of liver injury, evaluating ...
Copper ion content determination is commonly used in water quality, soil, food, feed, biological samples, alloy leachates, electroplating wastewater, and related systems. Chromogenic methods are suitable for rapid routine laboratory determination of copper content. However, different chromogenic ...
Alkaline phosphatase (ALP/AKP) activity assays are used to evaluate the hydrolytic capacity of samples toward phosphate monoesters. They are commonly applied in studies of osteogenic differentiation, bone metabolism, hepatobiliary injury, enzyme-labeled reactions, microbial metabolism, and ...