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Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.

5929 articles
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Functional Distinction among Orange G-6, EA36, and EA50 in the Papanicolaou Staining System

The core of Papanicolaou staining is not coloration by a single dye, but the formation of layered differences among nuclei, keratinized components, cytoplasm of mature squamous epithelial cells, and cytoplasm of non-keratinized cells through nuclear staining, keratinized cytoplasmic staining, ...

2026-05-25 07:21:07 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Staining-Based Differentiation of Collagen Fibers, Muscle Fibers, and Fibrin in Tissue Sections

In tissue sections, collagen fibers, muscle fibers, and fibrin may all appear as fibrous, fascicular, cord-like, or reticular structures. In routine hematoxylin and eosin (HE) staining, they often show varying degrees of eosinophilic red staining. Their differentiation should be based on tissue ...

2026-05-25 06:43:18 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Metabolic Division of Labor and Functional Differences Among IDH Isoenzymes

Isocitrate dehydrogenase (IDH) is a key enzyme family involved in the tricarboxylic acid cycle, NADPH supply, α-ketoglutarate generation, and cellular redox homeostasis. In mammalian cells, the major isoenzymes include IDH1, IDH2, and IDH3. IDH1 and IDH2 are NADP⁺-dependent enzymes and are ...

2026-05-25 06:42:44 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Metabolism and Oxidative Stress Detoxification, and Its Detection Applications

Aldehyde dehydrogenase (ALDH) is a class of oxidoreductases that use NAD+ or NADP+ as cofactors and mainly catalyze the oxidation of aldehyde substrates into corresponding carboxylic acids. Aldehydes can originate from ethanol metabolism, lipid peroxidation, sugar oxidation, drug metabolism, and ...

2026-05-25 06:03:30 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Construction and Evaluation Strategy of a Gentamicin-Induced Cell Injury Model

Gentamicin is an aminoglycoside antibiotic used in antibacterial therapy and cell culture contamination control. Because it can induce oxidative stress, mitochondrial dysfunction, lysosomal abnormalities, apoptosis, and necrosis-like injury, gentamicin is often used to construct injury models in ...

2026-05-25 05:42:05 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Staining Techniques and Experimental Applications in Sperm Morphology and Functional Evaluation

Sperm staining evaluation is a fundamental technique in male reproductive research, assisted reproduction experiments, animal breeding assessment, and reproductive toxicology analysis. Different staining methods can be used to assess sperm morphology, viability, plasma membrane integrity, ...

2026-05-25 03:42:25 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Structural and Performance Design of Acrylic Resins for Coatings: Monomer Composition, Key Parameters, and Film Formation/Curing Mechanisms

Acrylic resins are polymers or copolymers formed through the polymerization of acrylic acid, methacrylic acid, and their ester monomers as the main structural units. In coatings, acrylic resins are commonly used as film-forming materials or primary binder resins. They influence coating-film ...

2026-05-25 03:21:09 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Urease Reaction Systems, Urea Conversion, and Ammonia Nitrogen Quantitative Analysis

Urease catalyzes the hydrolysis of urea to produce ammonia and carbon dioxide. It is a key enzymatic node in soil nitrogen cycling, microbial metabolism, clinical testing, dairy quality analysis, fermentation process control, and environmental ammonia nitrogen monitoring. Detection systems ...

2026-05-25 03:04:03 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Guide to Epoxy Resin Performance Design: System Composition, Key Properties, Process Control, and Application Selection

The performance of epoxy resin is not determined by a single factor. For the same epoxy resin, changing the curing agent, filler, additive, or curing process may lead to a final material with completely different strength, toughness, heat resistance, chemical resistance, electrical insulation, ...

2026-05-25 03:04:03 Updated
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