1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Photoacoustic imaging technology is a new imaging technology developed in recent years. It is a hybrid mode of bio/medical imaging methods based on the photoacoustic effect. In photoacoustic imaging, pulsed laser light is usually required to illuminate the imaging site. The absorbed light energy ...
Asymmetric organocatalysis has emerged as a powerful synthetic tool that is complementary to metal-catalyzed reactions. Pioneering work in this area dates back to the 1970s in which Eder et al. and Hajos et al. separately reported an intramolecular asymmetric aldol reaction which employed ...
C(sp2)- and C(sp)-hybridized coupling reactions are established catalytic approaches. However, multi-step C(sp3)- and C(sp2)-coupling reactions of boronic acids and related derivatives are still limited by ineffective two-electron transmetalation reactions. These conventional protocols exhibit ...
Electron microscopy is essential when studying the complex structure of cells and organelles and studying cellular biological processes. Colloidal gold and its various derivatives have been the most widely used antigen markers in biological electron microscopy. These particles can be attached to ...
TEMPO (2,2,6,6-Tetramethylpiperidine 1-oxyl) and its derivatives play an important role as stabilizing nitroxide radicals for catalysts in organic oxidation reactions. TEMPO was first discovered by Lebedev and Kazarnovskii in 1960. The radical nature of the stabilizing radicals of TEMPO is ...
Ubiquitin is a small protein found in all eukaryotes. The covalent attachment of ubiquitin to intracellular proteins is called ubiquitination.
Nucleic acid therapy, as a prominent, novel and promising therapeutic approach, has potential in the treatment of many genetic diseases such as diabetes.
Macrophage effector function significantly influences the quality, duration, and magnitude of most inflammatory reactions. Traditionally, macrophages have been described as antigen-presenting phagocytes that secrete pro-inflammatory and antimicrobial mediators. Mounting evidence, however, ...
The Biginelli Reaction is an acid-catalyzed three-component reaction between an aromatic aldehyde, a β-keto ester, and a urea (e.g., urea, thiourea) to produce a tetrahydropyrimidinone with potential pharmaceutical applications.