1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
As a powerful tool in bioanalysis, immunoassays rely on specific reactions between antigens and selective antibodies and use different labels such as radioisotopes, enzymes, and fluorophores for signal development. In recent years, nanomaterials are increasingly replacing these molecular tags ...
Clemmensen reduction is an organic chemical reaction that uses zinc amalgam to reduce the carbonyl group in an aldehyde or ketone to a methylene group under heated reflux conditions in a concentrated hydrochloric acid solution. The reaction is named after its discoverer, Danish-American chemist ...
Cannizzaro reaction is non-enolizable aldehydes of hydrogen undergo intermolecular oxidation-reduction reactions under the action of strong bases, resulting in an organic disproportionation reaction of one molecule of carboxylic acid and one molecule of alcohol. When Italian chemist Stanislau ...
With rapid advances in the field of cross-coupling reactions of unactivated substrates catalyzed by metal complexes, the chemical market has been revolutionized by the introduction of a large library of achiral and chiral phosphine ligand compounds. Phosphine ligands have shown positive effects ...
Rapid pathogen detection and identification are of considerable importance in the early stages of food safety and treatment to avoid drug resistance. Modern laboratories use a number of molecular biology assays to distinguish these drug-resistant pathogenic strains from foodborne pathogens, ...
The basic process of hydrogenation has been used as an organic chemistry reaction to add hydrogen gas to compounds for various applications. While this process typically occurs in the presence of catalysts such as nickel or platinum, the use of gold as an alternative has drawn considerable ...
Karl Fischer titration for the determination of water is probably the best-known and most widely used titration method. The reaction mechanism has been well explored, and a large number of suitable reagents and instruments are available. The method is described in many regulations and guidelines ...
Antibo-drug conjugate (ADCs) combines the high specificity of antibodies with the strong cytotoxicity of small-molecule drugs. This combination combines the antibody's unique and very sensitive targeting ability to distinguish between healthy and cancerous tissue. It also has the cell-killing ...
BINOL and its derivatives are one of the most widely used types of ligands in asymmetric synthesis; being utilized in a variety of reactions including——Diels-Alder, carbonyl addition and reduction, Michael addition, and a variety of other reactions. Although great success has been achieved ...