Farampator - ≥98% , Glutamate receptor ionotropic AMPA positive allosteric modulator, CAS No.211735-76-1, Glutamate receptor ionotropic AMPA positive allosteric modulator

CAS: 211735-76-1 Cat. No.: F412201 Summenformel: C₁₂H₁₃N₃O₂ Molekulargewicht: 231.25

GRADE & PURITY ≥98%

Synonyms

Piperidine, 1-(2,1,3-benzoxadiazol-5-ylcarbonyl)- | Q5434818 | 7X6P5N8K2L | Org24448 | Org-24448 | BCP28990 | A935040 | AC-36657 | CX691;1-(benzofurazan-5-ylcarbonyl)piperidine | CX-691;Org24448 | EX-A4789 | 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methano

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

Information

Farampator (CX691, Org24448) is a positive modulator of AMPA receptor.

Specifications

Synonyme

Piperidine, 1-(2,1,3-benzoxadiazol-5-ylcarbonyl)- | Q5434818 | 7X6P5N8K2L | Org24448 | Org-24448 | BCP28990 | A935040 | AC-36657 | CX691;1-(benzofurazan-5-ylcarbonyl)piperidine | CX-691;Org24448 | EX-A4789 | 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methano

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

Farampator (CX691, Org24448) is a positive modulator of AMPA receptor.

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

POSITIVE ALLOSTERIC MODULATOR

Mechanismus der Wirkung

Glutamate receptor ionotropic AMPA positive allosteric modulator

Reinheit

≥98%

Produkteigenschaften

• ALogP: 1.5

Namen und Kennungen

• Pubchem Sid: 504762853
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504762853
• Kanonisches Lächeln: C1CCN(CC1)C(=O)C2=CC3=NON=C3C=C2
• IUPAC Name: 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methanone
• InChIKey: XFVRBYKKGGDPAJ-UHFFFAOYSA-N
• INCHI: 1S/C12H13N3O2/c16-12(15-6-2-1-3-7-15)9-4-5-10-11(8-9)14-17-13-10/h4-5,8H,1-3,6-7H2
• Isomere SMILES: C1CCN(CC1)C(=O)C2=CC3=NON=C3C=C2
• Molekulargewicht: 231.25
• Reaxy-Rn: 13677286
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13677286&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Piperidines
      • Subclass N-acylpiperidines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Piperidines
• Subclass: N-acylpiperidines
• Intermediate Tree Nodes: Not available
• Direct Parent: N-benzoylpiperidines
• Alternative Parents: Benzoxadiazoles Benzenoids Tertiary carboxylic acid amides Heteroaromatic compounds Furazans Oxacyclic compounds Azacyclic compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: N-benzoylpiperidine - Benzoxadiazole - Benzenoid - Azole - Furazan - Heteroaromatic compound - Oxadiazole - Tertiary carboxylic acid amide - Carboxamide group - Carboxylic acid derivative - Oxacycle - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as n-benzoylpiperidines. These are heterocyclic Compounds containing a piperidine ring conjugated to a benzyl group through one nitrogen ring atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

GRIA4 Tclin Glutamate receptor AMPA 3/4 (3 Activities)

Discover Target: GRIA4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Molekulargewicht: 231.250 g/mol
• XLogP3: 1.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 231.101 Da
• Monoisotopic Mass: 231.101 Da
• Topological Polar Surface Area: 59.200 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 291.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 211735-76-1, the molecular formula is C12H13N3O2, and the molecular weight is 231.25 g/mol. InChIKey XFVRBYKKGGDPAJ-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.