FITC-DEAE-dextran - 10 kDa , CAS No.F292058

CAS: F292058 Cat. No.: F292058

GRADE & PURITY 10 kDa

Synonyms

FITC-DEAE-dextran 10;ITC-diethylaminoethyl-dextran;Fluorescein isothiocyanate–Diethylaminoethyl–Dextran

Storage

Store at 2-8°C,Argon charged,Desiccated

Shipped In

Wet ice

Übersicht

FITC-DEAE-dextran is designed for special studies on membrane and transport properties in cells and tissues. Cationic (positively charged) diethylaminoethyl groups have been introduced into standard FITC-dextran. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-DEAE-dextrans from 4 kDa to 150 kDa. FITC-DEAE-dextrans are supplied as a yellow powder.Polysucrose are renamed from Ficoll™.

Structure

FITC-DEAE-dextrans are synthesized from well-characterised dextran fractions derived from Leuconostoc mesenteroides B512F. The degree of substitution for FITC lies between 0.001 – 0.008 and the limits for nitrogen content are 3-5% – corresponding to about one DEAE-substituent per three glucose units. The synthesis of DEAE-dextran introduces two types of DEAE-substituents into the dextran chain (see structure in datafile). The predominant substituent is the single tertiary group, but this reacts further particularly at higher degree of substitution to yield a “tandem” group containing a quaternary amine as well as the tertiary amine.

Spectral data

The excitation maximum for FITC-DEAE-dextran is 495 nm and the emission maximum is 520 nm. Maximum intensity is observed at pH 9.

Application

FITC-CM-dextran is mainly used for studying permeability and microcirculation. The diethylaminoethyl groups will impart an overall positive charge to the molecule, which may be valuable in gaining information on the permeability characteristics of cell membranes and tissues.

Specifications

Synonyme

FITC-DEAE-dextran 10;ITC-diethylaminoethyl-dextran;Fluorescein isothiocyanate–Diethylaminoethyl–Dextran

Spezifikationen & Reinheit

10 kDa

Storage

Store at 2-8°C,Argon charged,Desiccated

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Produkteigenschaften

Erregungs- und Emissionsbereiche

495 nm and 520 nm

Chemische und physikalische Eigenschaften

• Löslichkeit: dissolves readily in water.
• Empfindlichkeit: Moisture sensitive；light sensitive

Häufig gestellte Fragen

What are the CAS number, molecular formula and molecular weight?

The CAS Number is F292058.

How should this product be stored?

Store at 2–8 °C, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.