110 kDa for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 63 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
FITC-dextrans are synthesised by coupling fluoresceinyl isothiocyanate (5-isomer) to selected dextran fractions. All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. Aladdin produce FITC-dextrans from 4 kDa to 2000 kDa. FITC-dextrans are supplied as a yellow to orange powder.
Structure
Dextran is a branched polysaccharide elaborated by the bacteria Leuconostoc mesenteroides B512F. Dextran is essentially a linear glucose chain linked by α-D-(1 – 6) linkages. The degree of branching is about 5 %. The fluorescein moiety is attached by a stable thiocarbamoyl linkage and the labelling procedure does not lead to any depolymerization of the dextran. FITC-dextrans have from 0.002-0.008 mol FITC per glucose unit. These low levels of substitution confer minimal charges to dextran, which is an essential requirement for permeability studies.
Spectral data
FITC-dextran has an excitation maximum of 493 nm and an emission maximum of 518 nm. Maximal intensity is observed at pH >8.
Application
FITC-dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more.If you need larger quantities please contact us for a bulk quotation.
| Excitation and Emision Ranges | 493 nm and 518 nm |
|---|
| WGK Germany | 3 |
|---|
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2313245 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| B2313246 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| B2313247 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| B2313249 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| C2527204 | Certificate of Analysis | Nov 11, 2022 | F291064 |
| Solubility | dissolves readily in water H2O: 25 mg/mL |
|---|---|
| Sensitivity | Light & Heat & Moisture Sensitive |
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| 17. Baihao You, Chia-Hung Chen. (2024) Fluidic Membrane-Bound Protocells Enabling Versatile Assembly of Functional Nanomaterials for Biomedical Applications. ACS Nano, [PMID:39615041] [10.1021/acsnano.4c11349] |
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| 51. Kang Cheng, Guangbo He, Xiaxia Li, Yuqian Li, Xiaolin Cui, Xuefei Wu, Jau-Shyong Hong, Jie Zhao, Sheng Li, Yanjie Guo. (2025) Scorpion Venom Heat-Resistant Synthetic Peptide Alleviates DSS-Induced Colitis via α7nAChR-Mediated Modulation of the JAK2/STAT3 Pathway. Antioxidants, 14 (11): (1296). [PMID:41300453] [10.3390/antiox14111296] |
| 52. Xiaoyue Lai, Xiaoqin Wan, Xinyu Bao, Qingyuan Yang, Wei Zhang, Yan Tan, Xiaoshi Cai, Ziyang Wang, Yujie Li, Chun Liu, Zhongfang Deng, Pan Zheng, Dingyuan Tian, Ming Chen, Hongjun Yin, Gang Xu, Qi Huang, Zhihui Zhang, Hongmei Xia, Fang Deng. (2025) 5-Methoxytryptophan attenuates hypobaric hypoxia induced acute lung injury by alleviating lipid peroxidation via targeting peroxiredoxin 6. Redox Biology, [PMID:41270299] [10.1016/j.redox.2025.103922] |
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| 59. Honglin Zhou, Wenxiu Yuan, Jie Dong, Xiang Shao, Jinyun Chen, Fei Chang, Xinyi Cheng, Haoran Bai, Yujie Cheng, Qincheng Ma, Ying Wang, Jun Tang, Qingping Ke, Jianli Wang. (2026) Harnessing Pickering Emulsion Interfaces to Modulate Singlet Oxygen Generation for Highly Selective Oxidation of Cyclohexene. ACS Applied Materials & Interfaces, [PMID:41709818] [10.1021/acsami.5c26052] |
| 60. Junxia Zhang, Changyun Liu, Yupeng Wang, Yusi Chen, Haibao Shang, Wen Zheng, Li Jin, Peng Xie, Yingjia Li, Yahan Liu, Yunxiao Zhang, Yang Wang, Wei Zhao, Han Xiao, Guisong Wang, Xin Zhang, Xiaolei Yang, Erdan Dong, Yan Zhang. (2026) Bacteroides acidifaciens exacerbates cardiac ischemia/reperfusion injury via the microbial-host isozyme DPP4. Cell Host & Microbe, [PMID:41923637] [10.1016/j.chom.2026.03.012] |
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