GC7 Sulfate - 10mM in Water , CAS No.150417-90-6

CAS: 150417-90-6 Cat. No.: G421774 Summenformel: C₈H₂₂N₄O₄S Molekulargewicht: 270.35 PubChem CID: 131842088

GRADE & PURITY 10mM in Water

Synonyms

N1-guanyl-1,7-diaminoheptane SulfateGuanidine,(7-​aminoheptyl)​-​,sulfate (1:1) (9CI)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

GC7 Sulfate GC7 (N1-guanyl-1,7-diaminoheptane) Sulfate is an inhibitor of deoxyhypusine synthase (DHPS) . GC7 inhibits Neuroblastoma (NB) cell proliferation in a dose-dependent manner, through induction of the cell cycle inhibitor p21 and reduction of total and phosphorylated Rb proteins.

Targets

DHPS

Specifications

Synonyme

N1-guanyl-1,7-diaminoheptane SulfateGuanidine,(7-​aminoheptyl)​-​,sulfate (1:1) (9CI)

Spezifikationen & Reinheit

10mM in Water

Biochemische und physiologische Mechanismen

GC7 (N1-guanyl-1,7-diaminoheptane) Sulfate is an inhibitor of deoxyhypusine synthase (DHPS). GC7 inhibits Neuroblastoma (NB) cell proliferation in a dose-dependent manner, through induction of the cell cycle inhibitor p21 and reduction of total and phosph

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Produkteigenschaften

ALogP

-0.207

HBD-Zahl

3

Rotationsfähige Bindung

8

Namen und Kennungen

Pubchem Sid

528764579

Kanonisches Lächeln

C(CCCN)CCCN=C(N)N.OS(=O)(=O)O

IUPAC Name

2-(7-aminoheptyl)guanidine;sulfuric acid

InChIKey

MDDOWYFCKAAANU-UHFFFAOYSA-N

INCHI

1S/C8H20N4.H2O4S/c9-6-4-2-1-3-5-7-12-8(10)11;1-5(2,3)4/h1-7,9H2,(H4,10,11,12);(H2,1,2,3,4)

PubChem CID

131842088

Molekulargewicht

270.35

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic salts
    • Klasse Organic sulfate salts

• Kingdom: Organic compounds
• Superclass: Organic salts
• Klasse: Organic sulfate salts
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Organic sulfate salts
• Alternative Parents: Quaternary ammonium salts Organic sulfuric acids and derivatives Guanidines Propargyl-type 1,3-dipolar organic compounds Carboximidamides Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Organic cations
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organic sulfate salt - Organic sulfuric acid or derivatives - Quaternary ammonium salt - Guanidine - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Amine - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary amine - Organonitrogen compound - Organic oxygen compound - Primary aliphatic amine - Organic cation - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as organic sulfate salts. These are organic compounds containing a sulfate ion.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• DMSO (mg/ml) Maximale Löslichkeit: ＜1
• Wasser (mg/ml) Maximale Löslichkeit: 3
• Wasser (mM) Maximale Löslichkeit: 11.0967264656926
• Molekulargewicht: 270.350 g/mol
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 7
• Exact Mass: 270.136 Da
• Monoisotopic Mass: 270.136 Da
• Topological Polar Surface Area: 173.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 200.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3