GGsTop - Moligand™, 10 mM in DMSO , CAS No.926281-37-0

CAS: 926281-37-0 Cat. No.: G1494111 Summenformel: C₁₃H₁₈NO₇P Molekulargewicht: 331.26

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

GGsTop (Nahlsgen) is a potent, non-toxic, highly selective and irreversible γ-GGT inhibitor, with a K i of 170 μM for Human GGT. GGsTop shows a pK a of 9.71, also exhibits K on s of 150 and 51 M -1 s -1 against E.coli GGT and human GGT, respectively. GGsTop protects hepatic ischemia-reperfusion injury in rat model.

Specifications

Spezifikationen & Reinheit

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

INHIBITOR

Namen und Kennungen

• Isomere SMILES: COP(=O)(CCC(C(=O)O)N)OC1=CC=CC(=C1)CC(=O)O
• Molekulargewicht: 331.26
• Reaxy-Rn: 19207629
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19207629&ln=

Referenzen

1. Hanchen Shen, Lidong Du, Changhuo Xu, Bingzhe Wang, Qingqing Zhou, Ruquan Ye, Ryan T. K. Kwok, Jacky W. Y. Lam, Guichuan Xing, Jianwei Sun, Tzu-Ming Liu, Ben Zhong Tang.  (2024)  A Near-Infrared-II Excitable Pyridinium Probe with 1000-Fold ON/OFF Ratio for γ-Glutamyltranspeptidase and Cancer Detection.  ACS Nano,      [PMID:39058791] [10.1021/acsnano.4c03963]