Glycolide - ≥98% , CAS No.502-97-6

CAS: 502-97-6 Cat. No.: G156824 Summenformel: C₄H₄O₄ Molekulargewicht: 116.07 EG-Nummer: 207-954-9

GRADE & PURITY ≥98%

Synonyms

Acetic acid, bimol. cyclic ester | SCHEMBL15066 | 1,4-Dioxane-2,5-dione | AS-57477 | DTXSID8060115 | Glycolide | UNII-YRZ676PGU6 | Glycollide | EINECS 207-954-9 | FT-0606899 | 2,5-dioxo-1,4-dioxane

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Übersicht

Glycolide is a cyclic dimer of α-hydroxy acid that can be used in the formation of aliphatic polyester. It is synthesized by the dimerization of glycolic acid. It forms a low toxic synthetic biodegradable polymer that can be used in medical applications. It is majorly used in the formation of a highly crystalline poly(glycolide) by ring opening polymerization.

Application：

Glycolide can be used as a monomer in the preparation of poly(lactic-co-glycolide)(PGLA) via copolymerization with lactide monomer. PGLA is further used in the following applications:
Porous PGLA microsphere scaffolds are used in bone repair applications.
Encapsulated PGLA nanoparticles can be used in drug delivery and tissue engineering applications. Polymeric micro/nanoparticles made from PLGA have gained significant interest for their appealing characteristics, including biodegradability, biocompatibility, prolonged drug release, and safeguarding the drug against degradation.
It can also be used to synthesize poly(glycolide-caprolactone)(PGCL) copolymers applicable as bioabsorbable suture materials.

Specifications

Synonyme

Acetic acid, bimol. cyclic ester | SCHEMBL15066 | 1,4-Dioxane-2,5-dione | AS-57477 | DTXSID8060115 | Glycolide | UNII-YRZ676PGU6 | Glycollide | EINECS 207-954-9 | FT-0606899 | 2,5-dioxo-1,4-dioxane

Spezifikationen & Reinheit

≥98%

Storage

Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥98%

Namen und Kennungen

Pubchem Sid

488183682

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/488183682

Kanonisches Lächeln

C1C(=O)OCC(=O)O1

IUPAC Name

1,4-dioxane-2,5-dione

InChIKey

RKDVKSZUMVYZHH-UHFFFAOYSA-N

INCHI

1S/C4H4O4/c5-3-1-7-4(6)2-8-3/h1-2H2

Isomere SMILES

C1C(=O)OCC(=O)O1

Molekulargewicht

116.07

Reaxy-Rn

112109

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=112109&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Dioxanes
      • Subclass 1,4-dioxanes

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Dioxanes
• Subclass: 1,4-dioxanes
• Intermediate Tree Nodes: Not available
• Direct Parent: 1,4-dioxanes
• Alternative Parents: Dicarboxylic acids and derivatives Lactones Carboxylic acid esters Oxacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Dicarboxylic acid or derivatives - Para-dioxane - Lactone - Carboxylic acid ester - Oxacycle - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Aliphatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as 1,4-dioxanes. These are organic compounds containing 1,4-dioxane, an aliphatic six-member ring with two oxygen atoms in ring positions 1 and 4.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in Dimethylformamide
• Empfindlichkeit: Moisture & air & heat sensitive
• Siedepunkt (°C): 130℃
• Schmelzpunkt (°C): 82-86℃
• Molekulargewicht: 116.070 g/mol
• XLogP3: -0.200
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 116.011 Da
• Monoisotopic Mass: 116.011 Da
• Topological Polar Surface Area: 52.600 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 112.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 502-97-6, the molecular formula is C4H4O4, and the molecular weight is 116.07 g/mol. InChIKey RKDVKSZUMVYZHH-UHFFFAOYSA-N.