GNE-502 - ≥99% , CAS No.1953134-16-1

CAS: 1953134-16-1 Cat. No.: G648176 Summenformel: C₂₅H₃₀FN₃O₃S Molekulargewicht: 471.59

QUALITÄT & REINHEIT ≥99%

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

GNE-502 is an orally active and potent degrader for estrogen receptor ( ER ). GNE-502 can be used for the research of breast cancer

In Vivo

GNE-502 (10 and 100 mg/kg; p.o.) possesses sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model . GNE-502 shows dose dependent tumor growth inhibition at 10 mg/kg and 30 mg/kg, with tumor stasis at 100 mg/kg . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Mouse Dosage: 10 and 100 mg/kg (Pharmacokinetic Analysis) Administration: p.o.; single dosage Result: Possessed sufficient oral exposure to be tested in a WT MCF7 tumor xenograft model.

Form:Solid

IC50& Target:ER

Spezifikationen

Spezifikationen & Reinheit

≥99%

Biochemische und physiologische Mechanismen

GNE-502 is an orally active and potent degrader for estrogen receptor ( ER ). GNE-502 can be used for the research of breast cancer.

Storage

Protected from light,Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Reinheit

≥99%

Namen und Kennungen

Molekulargewicht

471.59

Chemische und physikalische Eigenschaften

• Löslichkeit: DMSO : 100 mg/mL (212.05 mM; Need ultrasonic)

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?80 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1953134-16-1, the molecular formula is C25H30FN3O3S, and the molecular weight is 471.59 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.