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· · COA & SDS für jedes Produkt verfügbar · Versand am selben Tag für Lagerartikel GNE-617 - 10mM in DMSO , CAS No.1362154-70-8
GRADE & PURITY 10mM in DMSO
Synonyms
Imidazo[1,2-a]pyridine-6-carboxamide,N-[[4-[(3,5-difluorophenyl)sulfonyl]phenyl]methyl]-
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Übersicht Information
GNE-617 GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.
Targets
NAMPT (Cell-free assay) 5 nM
Specifications Synonyme
Imidazo[1,2-a]pyridine-6-carboxamide,N-[[4-[(3,5-difluorophenyl)sulfonyl]phenyl]methyl]-
Spezifikationen & Reinheit
10mM in DMSO
Biochemische und physiologische Mechanismen
GNE-617 is a highly potent inhibitor of NAMPT activity with an IC50 of 5 nM.
Verschickt in
Dry ice packs + Cold packs
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Produkteigenschaften Namen und Kennungen Kanonisches Lächeln
C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F
IUPAC Name
N-[[4-(3,5-difluorophenyl)sulfonylphenyl]methyl]imidazo[1,2-a]pyridine-6-carboxamide
InChIKey
XRDVXQQZLHVEQZ-UHFFFAOYSA-N
INCHI
1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27)
Isomere SMILES
C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22322434&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Klasse Imidazopyridines Subclass Not available Intermediate Tree Nodes Not available Direct Parent Imidazopyridines Alternative Parents Benzenesulfonyl compounds Pyridinecarboxamides Imidazo[1,2-a]pyridines Fluorobenzenes Aryl fluorides N-substituted imidazoles Vinylogous amides Sulfones Heteroaromatic compounds Secondary carboxylic acid amides Azacyclic compounds Organooxygen compounds Hydrocarbon derivatives Organonitrogen compounds Organic oxides Organofluorides Molecular Framework Aromatic heteropolycyclic compounds Substituents Imidazo[1,2-a]pyridine - Benzenesulfonyl group - Imidazopyridine - Pyridinecarboxamide - Pyridine carboxylic acid or derivatives - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - N-substituted imidazole - Benzenoid - Pyridine - Azole - Heteroaromatic compound - Imidazole - Vinylogous amide - Sulfonyl - Sulfone - Carboxamide group - Secondary carboxylic acid amide - Azacycle - Carboxylic acid derivative - Organofluoride - Organohalogen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Organic oxide - Aromatic heteropolycyclic compound Beschreibung This compound belongs to the class of organic compounds known as imidazopyridines. These are organic polycyclic compounds containing an imidazole ring fused to a pyridine ring. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Pyridine is a 6-membered ring consisting of five carbon atoms and one nitrogen center. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften DMSO (mg/ml) Maximale Löslichkeit 42 DMSO (mM) Maximale Löslichkeit 98.2640026203734 Wasser (mg/ml) Maximale Löslichkeit ＜1 Molekulargewicht 427.400 g/mol XLogP3 3.500 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 5 Exact Mass 427.08 Da Monoisotopic Mass 427.08 Da Topological Polar Surface Area 88.900 Ų Heavy Atom Count 30 Formal Charge 0 Complexity 699.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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