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Deubiquitinase
GSK2643943A - 10mM in DMSO , CAS No.2449301-27-1

GSK2643943A - 10mM in DMSO , CAS No.2449301-27-1

Name: GSK2643943A - 10mM in DMSO , CAS No.2449301-27-1
SKU: G422830
Availability: InStock

CAS: 2449301-27-1 Cat. No.: G422830 Summenformel: C₁₇H₁₂FN₃ Molekulargewicht: 277.3

COA

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GSK2643943A - 10mM in DMSO CAS No(2449301-27-1) by Aladdin Scientific

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GRADE & PURITY 10mM in DMSO

Synonyms

1H-Indole-3-carbonitrile,2-amino-6-[2-(3-fluorophenyl)ethenyl]-

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht Specifications Produkteigenschaften Namen und Kennungen Documentation Advanced Data 3D-Struktur Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Lösungsrechner Bewertungen

🧪

Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Information

GSK2643943A is an inhibitor ofdeubiquitylating enzyme (DUB)with IC50 of 160 nM forUSP20/Ub-Rho.

Targets

USP20/Ub-Rho (Cell-free assay) 160 nM

Specifications

Synonyme

1H-Indole-3-carbonitrile,2-amino-6-[2-(3-fluorophenyl)ethenyl]-

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

GSK2643943A is an inhibitor of deubiquitylating enzyme (DUB) with IC50 of 160 nM for USP20/Ub-Rho.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Produkteigenschaften

ALogP

3.571

HBD-Zahl

Rotationsfähige Bindung

Namen und Kennungen

Pubchem Sid

528764684

Kanonisches Lächeln

C1=CC(=CC(=C1)F)C=CC2=CC3=C(C=C2)C(=C(N3)N)C#N

IUPAC Name

2-amino-6-[(E)-2-(3-fluorophenyl)ethenyl]-1H-indole-3-carbonitrile

InChIKey

CGXBPMZRTMXEIA-SNAWJCMRSA-N

INCHI

1S/C17H12FN3/c18-13-3-1-2-11(8-13)4-5-12-6-7-14-15(10-19)17(20)21-16(14)9-12/h1-9,21H,20H2/b5-4+

Molekulargewicht

277.3

Reaxy-Rn

38910864

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38910864&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D-Struktur

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	Datum	Artikel
H2401526	Certificate of Analysis	Jun 04, 2026	G422830

Chemische und physikalische Eigenschaften

DMSO (mg/ml) Maximale Löslichkeit	55
DMSO (mM) Maximale Löslichkeit	198.341146772449
Wasser (mg/ml) Maximale Löslichkeit	＜1
Molekulargewicht	277.290 g/mol
XLogP3	4.300
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	2
Exact Mass	277.102 Da
Monoisotopic Mass	277.102 Da
Topological Polar Surface Area	65.600 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	441.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

Lösungsrechner

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