Guan-fu base A - ≥98% , CAS No.1394-48-5

CAS: 1394-48-5 Cat. No.: G302802 Summenformel: C₂₄H₃₁NO₆ Molekulargewicht: 429.51 PubChem CID: 101603171

GRADE & PURITY ≥98%

Synonyms

Acehytisine; Kwan-fu base A; (2alpha,11alpha,13R)-Hetisan-2,11,13,14-tetrol 2,13-diacetate

Storage

Store at 2-8°C,Protected from light

Shipped In

Wet ice

Übersicht

product description：

Guanfu base A is an antiarrhythmic alkaloid isolated from Aconitum coreanum and is a potent noncompetitive CYP2D6 inhibitor, with a Ki of 1.20 μM in human liver microsomes (HLMs) and a Ki of 0.37 μM for the human recombinant form (rCYP2D6). Guanfu base A is also a potent competitive inhibitor of CYP2D in monkey (Ki of 0.38 μM) and dog (Ki of 2.4 μM) microsomes. Guanfu base A also inhibits HERG channel current.

Specifications

Synonyme

Acehytisine; Kwan-fu base A; (2alpha,11alpha,13R)-Hetisan-2,11,13,14-tetrol 2,13-diacetate

Spezifikationen & Reinheit

≥98%

Storage

Store at 2-8°C,Protected from light

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥98%

Namen und Kennungen

• Pubchem Sid: 504772770
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504772770
• Kanonisches Lächeln: CC(=O)OC1CC2(CN3C4C2C5(C1)C3C6(C(C7C(C5C6(C4)CC7=C)O)OC(=O)C)O)C
• IUPAC Name: [(1S,3S,5S,8S,9R,11R,14R,16S,17R,18S,19S)-10-acetyloxy-9,19-dihydroxy-5-methyl-12-methylidene-7-azaheptacyclo[9.6.2.01,8.05,17.07,16.09,14.014,18]nonadecan-3-yl] acetate
• InChIKey: OGNUSOJAYIHLNS-CGMBEVFJSA-N
• INCHI: 1S/C24H31NO6/c1-10-5-22-8-14-17-21(4)6-13(30-11(2)26)7-23(17)18(22)16(28)15(10)19(31-12(3)27)24(22,29)20(23)25(14)9-21/h13-20,28-29H,1,5-9H2,2-4H3/t13-,14-,15+,16+,17+,18+,19?,20-,21+,22+,23-,24-/m0/s1
• Isomere SMILES: CC(=O)O[C@H]1C[C@@]2(CN3[C@@H]4[C@H]2[C@]5(C1)[C@H]3[C@]6(C([C@H]7[C@H]([C@@H]5[C@]6(C4)CC7=C)O)OC(=O)C)O)C
• PubChem CID: 101603171
• Molekulargewicht: 429.51

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Moisture sensitive；Light sensitive

Häufig gestellte Fragen

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C, protected from light. The material is light-sensitive — keep it in its original opaque or amber container.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1394-48-5, the molecular formula is C24H31NO6, and the molecular weight is 429.51 g/mol. InChIKey OGNUSOJAYIHLNS-CGMBEVFJSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.