H3B-120 - 10mM in DMSO , CAS No.2194903-42-7

CAS: 2194903-42-7 Cat. No.: H422634 Summenformel: C19H24N4O2S Molekulargewicht: 372.48
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GRADE & PURITY 10mM in DMSO
Synonyms
N1-Methyl-N4-(4-methyl-2-thiazolyl)-N1-(phenylmethyl)-1,4-piperidinedicarboxamide
Storage
Protected from light,Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
Deutschland (EU)
USA*
Price
Qty
1ml
H422634-1ml
—
2 Auf Lager

131,81€

192,55€
Speichern 60,74 € (31.55%)
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Information

H3B-120 H3B-120 is a competitive, selective and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 1.5 μM and Ki of 1.4 μM. H3B-120 exhibits anti-tumor activity.

Targets

CPS1 (Cell-free assay); CPS1 (Cell-free assay) 1.4 μM(Ki); 1.5 μM

Specifications

Synonyme
N1-Methyl-N4-(4-methyl-2-thiazolyl)-N1-(phenylmethyl)-1,4-piperidinedicarboxamide
Spezifikationen & Reinheit
10mM in DMSO
Biochemische und physiologische Mechanismen
H3B-120 is a competitive, selective and allosteric inhibitor of carbamoyl phosphate synthetase 1 (CPS1) with IC50 of 1.5 μM and Ki of 1.4 μM. H3B-120 exhibits anti-tumor activity.
Storage
Protected from light,Store at -80°C
Verschickt in
Dry ice packs + Cold packs
Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.
Aktionsart
INHIBITOR
Produkteigenschaften
ALogP
1.901
hba_count
3
HBD-Zahl
1
Rotationsfähige Bindung
4
Namen und Kennungen
Pubchem Sid
Kanonisches Lächeln
CC1=CSC(=N1)NC(=O)C2CCN(CC2)C(=O)N(C)CC3=CC=CC=C3
IUPAC Name
1-N-benzyl-1-N-methyl-4-N-(4-methyl-1,3-thiazol-2-yl)piperidine-1,4-dicarboxamide
InChIKey
ZEVOZXRSCSSPAO-UHFFFAOYSA-N
INCHI
1S/C19H24N4O2S/c1-14-13-26-18(20-14)21-17(24)16-8-10-23(11-9-16)19(25)22(2)12-15-6-4-3-5-7-15/h3-7,13,16H,8-12H2,1-2H3,(H,20,21,24)
Isomere SMILES
CC1=CSC(=N1)NC(=O)C2CCN(CC2)C(=O)N(C)CC3=CC=CC=C3
Molekulargewicht
372.48
Reaxy-Rn
35902200
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=35902200&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
KlassePiperidines
SubclassPiperidinecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentPiperidinecarboxamides
Alternative Parents N-arylamides  2,4-disubstituted thiazoles  N-acyl amines  Benzene and substituted derivatives  Heteroaromatic compounds  Ureas  Sulfenyl compounds  Propargyl-type 1,3-dipolar organic compounds  Carboxylic acid amides  Carboximidamides  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Piperidinecarboxamide - 1-piperidinecarboxamide - N-arylamide - 2,4-disubstituted 1,3-thiazole - Benzenoid - N-acyl-amine - Monocyclic benzene moiety - Heteroaromatic compound - Thiazole - Azole - Urea - Carbonic acid derivative - Carboxamide group - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Sulfenyl compound - Carboximidamide - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
BeschreibungThis compound belongs to the class of organic compounds known as piperidinecarboxamides. These are compounds containing a piperidine ring substituted with a carboxamide functional group.
External Descriptors Not available
3D-Struktur
Interaktives chemisches Strukturmodell





Wirkungsmechanismen
Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDatumArtikel
F2417499Certificate of AnalysisMay 11, 2026 H422634
Chemische und physikalische Eigenschaften
EmpfindlichkeitLight sensitive
DMSO (mg/ml) Maximale Löslichkeit74
DMSO (mM) Maximale Löslichkeit198.668384879725
Wasser (mg/ml) Maximale Löslichkeit<1
Molekulargewicht372.500 g/mol
XLogP32.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass372.162 Da
Monoisotopic Mass372.162 Da
Topological Polar Surface Area93.800 Ų
Heavy Atom Count26
Formal Charge0
Complexity490.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Lösungsrechner
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