hCG Antibody - Primärer Antikörper, specific to hCG, Rabbit IgG

Cat. No.: Ab106958

GRADE & PURITY Carrier Free, Validated, ExactAb™, 0.15 mg/mL

Application

IHC

Host species

Kaninchen

Reactive species

Mensch

Isotype

Rabbit IgG

Conjugation

Unconjugated

Übersicht

Rabbit anti Human hCG Antibody, Polyclonal, could be used for IHC and so on.
Application
IHC: 1/50-1/100
Relevance
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non pregnant urine and sera. It rises sharply during pregnancy. HCG is composed of two non identical, non covalently linked polypeptide chains designated as the a and b subunits. The a subunit of HCG is nearly identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). A germ cell tumor which is positive for cytokeratin, placental alkaline phosphatase (PLAP) and HCG but negative for EMA and AFP is probably a choriocarcinoma.

Specifications

Product Name

hCG Antibody - Primärer Antikörper, specific to hCG, Rabbit IgG

Synonyme

anterior pituitary glycoprotein hormones common subunit alpha antibody | CG alpha antibody | CG-ALPHA antibody | CGB antibody | CGB3 antibody | CGB5 antibody | CGB7 antibody | choriogonadotropin alpha chain antibody | Chorionic gonadotrophin chain beta an

Spezifikationen & Reinheit

ExactAb™, Validated, Carrier Free, 0.15 mg/mL

Wirtsspezies

Kaninchen

Spezifität

hCG

Immunogen

A synthetic peptide corresponding to residues of hCG (AA 1-100).

Positive Kontrolle

IHC: Human placenta tissue.

Konjugation

Unconjugated

Note

Carrier Free, ExactAb™, Validated

Isotyp

Rabbit IgG

SDS-PAGE

150 kDa

Verfahren zur Reinigung

Protein A purified

Konzentration

0.15 mg/mL

Lagerung und Versand

Form

Liquid

Storage

Store at -20°C,Avoid repeated freezing and thawing

Verschickt in

Ice chest + Ice pads

Stabilität und Lagerung

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Bilder

IHC: hCG Antibody (Ab106958) ​

hCG Antibody (Ab106958) - IHC
Immunohistochemistry analysis of paraffin-embedded human placenta tissue labelling hCG with hCG Antibody (Ab106958) at 1/100 dilution. The section was incubated with Ab106958 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Anwendung

• Anwendung: Dilution info
• IHC:

  1/50 - 1/100;

Zugehörige Ziele (menschlich)

CGA Tbio Glycoprotein hormones alpha chain (0 Activities)

Discover Target: CGA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Wirkungsmechanismen

Häufig gestellte Fragen

What does ExactAb? mean?

ExactAb? indicates the product has been validated for use in rigorous antibody validation workflows. Validation may include positive/negative control samples, signal-to-noise testing, and protocol-specific QC. Lot-specific test data is published on the Certificate of Analysis where available.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (hCG Antibody); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.