Hippuric acid - 10mM in DMSO , CAS No.495-69-2

CAS: 495-69-2 Cat. No.: H424276 Molecular Weight: 179.17 Beilstein Registry Number: 1073987 EC Number: 207-806-3
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GRADE & PURITY 10mM in DMSO
Synonyms
N-Benzoylglycine | n-benzoyl-glycine | Tox21_111710_1 | (benzoylamino)-Acetate | 2-(Phenylformamido)Acetic Acid | Bz-Gly-OH | Benzoylglycin | Benzoylglycocoll | FT-0660260 | NCGC00159486-02 | TimTec1_002805 | Acido ippurico [Italian] | HIPPURIC ACID [INCI
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
H424276-1ml
1

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 21 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
N-Benzoylglycine | n-benzoyl-glycine | Tox21_111710_1 | (benzoylamino)-Acetate | 2-(Phenylformamido)Acetic Acid | Bz-Gly-OH | Benzoylglycin | Benzoylglycocoll | FT-0660260 | NCGC00159486-02 | TimTec1_002805 | Acido ippurico [Italian] | HIPPURIC ACID [INCI
Specifications & Purity
10mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Canonical SmilesC1=CC=C(C=C1)C(=O)NCC(=O)O
IUPAC Name2-benzamidoacetic acid
InChIKeyQIAFMBKCNZACKA-UHFFFAOYSA-N
INCHI1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)
Isomeric SMILES C1=CC=C(C=C1)C(=O)NCC(=O)O
WGK Germany 3
RTECS MR8150000
Molecular Weight 179.17
Beilstein 1073987
Reaxy-Rn 1073987
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1073987&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassBenzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Benzamides - Hippuric acids and derivatives
Direct ParentHippuric acids
Alternative Parents N-acyl-alpha amino acids  Benzoyl derivatives  Secondary carboxylic acid amides  Monocarboxylic acids and derivatives  Carboxylic acids  Organopnictogen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Hippuric acid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Benzoyl - Carboxamide group - Secondary carboxylic acid amide - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic nitrogen compound - Carbonyl group - Organic oxygen compound - Organooxygen compound - Aromatic homomonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as hippuric acids. These are compounds containing hippuric acid, which consists of a of a benzoyl group linked to the N-terminal of a glycine.
External Descriptors N-acylglycine
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
DHFR Tclin Dihydrofolate reductase (3072 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
AKR1B1 Tclin Aldose reductase (1404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KYNU Tchem Kynureninase (42 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
LMNA Tbio Prelamin-A/C (36751 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A8 Tclin Solute carrier family 22 member 8 (241 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RUNX1 Tbio Runt-related transcription factor 1/Core-binding factor subunit beta (7867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Abcb1b P-glycoprotein 1 (174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HD1 Histone deacetylase (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a20 Solute carrier family 22 member 20 (86 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Slc22a6 Solute carrier family 22 member 6 (141 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate TypeDateItem
J2210007Certificate of AnalysisMay 13, 2026 H424276
Chemical and Physical Properties
SensitivityMoisture sensitive.
Melt Point(°C)188-191°C
Molecular Weight179.170 g/mol
XLogP30.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass179.058 Da
Monoisotopic Mass179.058 Da
Topological Polar Surface Area66.400 Ų
Heavy Atom Count13
Formal Charge0
Complexity197.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Shuai Zhang, Mei Deng, Ruifen Zhang, Xuchao Jia, Fei Huang, Dong Zhao, Lihong Dong, Jianwei Chi, Zhida Sun, Qin Ma, Mingwei Zhang.  (2023)  Modulation effect of black rice dietary fiber on the metabolism and fermentation of cyanidin-3-glucoside in an in vitro human colonic model.  Food & Function,  14  (14): (6707-6717).  [PMID:37404037] [10.1039/D3FO00955F]
2. Wei Jia, Xin Wang.  (2023)  3-Chloropropane-1,2-diol exposure adversely influenced the bio-accessibility signatures of digested infant foods by suppressing the destabilization of α-lactalbumin and d-aspartate oxidase in a dose-dependent manner.  FOOD CHEMISTRY,      [PMID:37385056] [10.1016/j.foodchem.2023.136729]
3. Qi Liu, Shan Shao, Jingyu Bao, Syed Jalil Shah, Shumin Yue, Xinqi Luan, Qing Liu, Linguang Xing, Zhongfeng Shi, Zhenxia Zhao, Zhongxing Zhao.  (2023)  High accuracy prediction of dipeptide angiotensin-converting enzyme (ACE) inhibitory activity by improving the credibility of the 3D-quantitative structure-activity relationship (3D-QSAR) model database and investigating inhibition mechanism.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2023.06.010]
4. Chenhui Gu, Xuewen Hu, Baixi Shan, Xiaojing Wu, Jun Chen.  (2023)  Targeted and non-targeted metabolomics uncovering the effects of Er-Miao-Wan formula on rats with hyperuricemia.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:36731256] [10.1016/j.jpba.2023.115246]
5. Xueyan Gou, Fenglin Ran, Jinru Yang, Yanrong Ma, Xin’an Wu.  (2022)  Construction and Evaluation of a Novel Organic Anion Transporter 1/3 CRISPR/Cas9 Double-Knockout Rat Model.  Pharmaceutics,  14  (11): (2307).  [PMID:36365126] [10.3390/pharmaceutics14112307]
6. Zeng Sen, Hou Yaqi, Zhou Yaming, Zhou Xi, Ye Shefang, Wang Miao, Ren Lei.  (2022)  Adsorptive removal of uremic toxins using Zr-based MOFs for potential hemodialysis membranes.  JOURNAL OF MATERIALS SCIENCE,  57  (4): (2909-2923).  [PMID:] [10.1007/s10853-021-06783-4]
7. Haipeng Ye, Ji Shao, Yanpeng Shi, Siwei Tan, Kewen Su, Ling Zhang, Xiaoyue Shan.  (2021)  Magnetic molecularly imprinted polymers for extraction of S-phenylmercapturic acid from urine samples followed by high-performance liquid chromatography.  JOURNAL OF MOLECULAR RECOGNITION,  34  (11): (e2930).  [PMID:34432338] [10.1002/jmr.2930]
8. Junjie Yu, Junjie Wu, Dewei Xie, Lei Du, Ya-Jie Tang, Jingli Xie, Dongzhi Wei.  (2020)  Characterization and rational design for substrate specificity of a prolyl endopeptidase from Stenotrophomonas maltophilia.  ENZYME AND MICROBIAL TECHNOLOGY,      [PMID:32527522] [10.1016/j.enzmictec.2020.109548]
9. Bo Chen, Jie Zhou, Qilu Meng, Yang Zhang, Shihua Zhang, Liang Zhang.  (2018)  Comparative analysis of fecal phenolic content between normal and obese rats after oral administration of tea polyphenols.  Food & Function,  (9): (4858-4864).  [PMID:30156246] [10.1039/C8FO00609A]
10. De-Chun Zhang, Dou Ma, Xia Li.  (2017)  Multiple modulator-induced syntheses, crystal structures, and luminescent properties on hippuric acid and bovine serum albumin of Ln(III) complexes with 2,2′-oxybis(benzoic acid).  JOURNAL OF COORDINATION CHEMISTRY,      [PMID:] [10.1080/00958972.2017.1381881]
11. Chunyan Qi, Guimei Lin, Rong Zhang, Wenjuan Wu.  (2017)  Studies on the Bioactivities of ACE-inhibitory Peptides with Phenylalanine C-terminus Using 3D-QSAR, Molecular Docking and in vitro Evaluation.  Molecular Informatics,  36  (9): (1600157).  [PMID:28452129] [10.1002/minf.201600157]
12. Xue-jia Zhai, Fen Chen, Chao-ran Zhu, Yong-ning Lu.  (2015)  A simple LC-MS/MS method for quantitative analysis of underivatized neurotransmitters in rats urine: assay development, validation and application in the CUMS rat model.  BIOMEDICAL CHROMATOGRAPHY,  29  (11): (1737-1743).  [PMID:25944269] [10.1002/bmc.3487]
13. Tiesheng Hu, Zhipeng Li, Tingting Wang, Heping Zeng.  (2015)  Synthesis and Properties of Photochromic Diarylethenes Bearing Thiazole Moiety.  JOURNAL OF HETEROCYCLIC CHEMISTRY,  53  (1): (109-116).  [PMID:] [10.1002/jhet.2037]
14. Pui-Kei Lee, Co Vanessa Anna, Yang Yang, Murphy Lam Yim Wan, Hani El-Nezami, Danyue Zhao.  (2024)  Bioavailability and interactions of schisandrin B with 5-fluorouracil in a xenograft mouse model of colorectal cancer.  FOOD CHEMISTRY,      [PMID:39332376] [10.1016/j.foodchem.2024.141371]
15. Shengdi Gu, Junjie Yu, Lei Du, Daihui Zhang, Li Zhao, Jingli Xie.  (2024)  Characterization, Semirational Design for pH Robustness, and the Application in Bioactive Peptide Production of a X-Prolyl Dipeptidyl Aminopeptidase from Lactococcus lactis MY-3.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:38519413] [10.1021/acs.jafc.4c00146]
16. Xin-Yu Zu, Ya-Nan Zhao, Yan Liang, Ying-Qiu Li, Chen-Ying Wang, Xiang-Zhong Zhao, Hua Wang.  (2024)  Research on the screening and inhibition mechanism of angiotensin I-converting enzyme (ACE) inhibitory peptides from tuna dark muscle.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2024.103956]
17. Dan Li, Liangchen Long, Wei Xia, Weixin Zhao, Likui Feng, Xinhui Xia, Shufei He, Yu Liu, Shijie You, Liangliang Wei.  (2025)  Utilization of UV/VUV irradiation for removal of human body fluids related pollutants in swimming pool water.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:39952138] [10.1016/j.jhazmat.2025.137549]
18. Hongmei Gao, Yourong Zhao, Yuhong Xie, Yiying Wang, Jie Che, Daojiang Gao, Zhanglei Ning.  (2025)  A Ratiometric Fluorescent Probe Based on CDs-Functionalized UiO-66 for Efficient Detection of Uric Acid.  Chemosensors,  13  (9): (340).  [PMID:] [10.3390/chemosensors13090340]
19. Shangguang Du, Xutang Tu, Xiaohua Duan, Hao Wan, Zuozuo Ai, Jun Luo, Zhengrong Zou, Liping Luo.  (2024)  Rapid Analysis of Colonic Metabolomics in High-Fat Diet Mice by Extraction Electrospray Ionization Mass Spectrometry (EESI-MS).  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:39083356] [10.1021/acs.jafc.4c05629]
20. Cailing Yu, Xinyu Zu, Yan Liang, Xiangzhong Zhao, Yingqiu Li, Chenying Wang, Hua Wang.  (2025)  A highly efficient method for screening dual-target inhibitory peptides against angiotensin I-converting enzyme and α-amylase from Chlorella using an enzyme-immobilized affinity membrane.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41224052] [10.1016/j.ijbiomac.2025.148954]
21. Xiaoyue Shan, Ji Shao, Ling Zhang, Yan Jin, Siwei Tan, Haipeng Ye, Luoxian Yang.  (2026)  Preparation of activated carbon and β-cyclodextrin modified magnetic nanoparticles for extraction and determination of hippuric acid in urine samples.  Talanta Open,      [PMID:] [10.1016/j.talo.2026.100613]
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