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HP211206 is a SARS-CoV-2 main protease ( M pro ) PROTAC degrader. HP211206 effectively degrades SARS-CoV-2 M pro and its drug-resistant mutants. HP211206 has an IC 50 of 181.9 nM and a DC 50 of 621 nM for M pro. HP211206 has antiviral activity. (Pink: H117 ; Black: linker ; Blue: E3 ligase ligand ).
| CAS | H1422506 |
|---|---|
| Storage | Store at -20°C |
| Verschickt in | Ice chest + Ice pads |
| Product Description | HP211206 is a SARS-CoV-2 main protease ( M pro ) PROTAC degrader. HP211206 effectively degrades SARS-CoV-2 M pro and its drug-resistant mutants. HP211206 has an IC 50 of 181.9 nM and a DC 50 of 621 nM for M pro. HP211206 has antiviral activity. (Pink: H117 ; Black: linker ; Blue: E3 ligase ligand ). |