(-)-Hydroxycitric acid - ≥98% , CAS No.27750-10-3

CAS: 27750-10-3 Cat. No.: H650021 Summenformel: C₆H₈O₈ Molekulargewicht: 208.12 PubChem CID: 185620

GRADE & PURITY ≥98%

Synonyms

F82031 | (-)-HYDROXYCITRIC ACID CALCIUM SALT | EC 200-157-7 | Haes cpd | UNII-8W94T9026R | Hydroxycitric acid ethylenediamine salt | 7A3 | (-)-HYDROXYCITRIC ACID (CONSTITUENT OF GARCINIA CAMBOGIA AND GARCINIA INDICA) | (1S,2S)-1,2-dihydroxy-1,2,3-propanet

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

(-)-Hydroxycitric acid (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. (-)-Hydroxycitric acid is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses the fatty acid synthesis, lipogenesis, food intake, and induced weight loss.

Form:Solid

Specifications

Synonyme

F82031 | (-)-HYDROXYCITRIC ACID CALCIUM SALT | EC 200-157-7 | Haes cpd | UNII-8W94T9026R | Hydroxycitric acid ethylenediamine salt | 7A3 | (-)-HYDROXYCITRIC ACID (CONSTITUENT OF GARCINIA CAMBOGIA AND GARCINIA INDICA) | (1S,2S)-1,2-dihydroxy-1,2,3-propanet

Spezifikationen & Reinheit

≥98%

Biochemische und physiologische Mechanismen

(-)-Hydroxycitric acid (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia . (-)-Hydroxycitric acid is a potent and competitive inhibitor of ATP citrate lyase . (-)-Hydroxycitric acid suppresses the fatty acid synthesis, lipogenesis,

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

INHIBITOR

Reinheit

≥98%

Namen und Kennungen

• Kanonisches Lächeln: C(C(=O)O)C(C(C(=O)O)O)(C(=O)O)O
• IUPAC Name: (1S,2S)-1,2-dihydroxypropane-1,2,3-tricarboxylic acid
• InChIKey: ZMJBYMUCKBYSCP-CVYQJGLWSA-N
• INCHI: 1S/C6H8O8/c7-2(8)1-6(14,5(12)13)3(9)4(10)11/h3,9,14H,1H2,(H,7,8)(H,10,11)(H,12,13)/t3-,6+/m1/s1
• Isomere SMILES: C(C(=O)O)[C@]([C@@H](C(=O)O)O)(C(=O)O)O
• Alternative CAS-Nummer: 6205-14-7,27750-10-3,4373-35-7
• PubChem CID: 185620
• MeSH-Eintrag: (+)-allohydroxycitric acid;allo-2-hydroxycitric acid;D-threo-pentaric acid, 3-C-carboxy-2-deoxy-;garcinia acid;HAES cpd;hibiscus acid;hydroxycitrate;hydroxycitric acid;hydroxycitric acid ethylenediamine salt;hydroxycitric acid, erythro-(D)-isomer;hydroxyc
• Molekulargewicht: 208.12

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Carboxylic acids and derivatives
      • Subclass Tricarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Carboxylic acids and derivatives
• Subclass: Tricarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Tricarboxylic acids and derivatives
• Alternative Parents: Beta hydroxy acids and derivatives Monosaccharides Alpha hydroxy acids and derivatives Tertiary alcohols Secondary alcohols 1,2-diols Carboxylic acids Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Tricarboxylic acid or derivatives - Beta-hydroxy acid - Monosaccharide - Hydroxy acid - Alpha-hydroxy acid - Tertiary alcohol - Secondary alcohol - 1,2-diol - Carboxylic acid - Hydrocarbon derivative - Organic oxygen compound - Organooxygen compound - Carbonyl group - Alcohol - Organic oxide - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as tricarboxylic acids and derivatives. These are carboxylic acids containing exactly three carboxyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Zugehörige Ziele (menschlich)

ACLY Tclin ATP-citrate synthase (1 Activities)

Discover Target: ACLY

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACLY Tclin ATP-citrate synthase (168 Activities)

Discover Target: ACLY

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: H2O : 5 mg/mL (24.02 mM; ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C)
• Molekulargewicht: 208.120 g/mol
• XLogP3: -2.600
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 208.022 Da
• Monoisotopic Mass: 208.022 Da
• Topological Polar Surface Area: 152.000 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 271.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1