Ilorasertib - Moligand™, 10 mM in DMSO , CAS No.1227939-82-3

CAS: 1227939-82-3 Cat. No.: I1498387 Molecular Weight: 488.5 PubChem CID: 46207586

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Ilorasertib (ABT-348) is a potent, orally active and ATP-competitive aurora inhibitor with IC 50 s of116, 5, 1 nM for aurora A , aurora B , aurora C , respectively. Ilorasertib also is a potent VEGF , PDGF inhibitor. Ilorasertib has the potential for the research of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Product Properties

• ALogP: 3

Names and Identifiers

• Isomeric SMILES: C1=CC(=CC(=C1)F)NC(=O)NC2=CC=C(C=C2)C3=CSC4=C3C(=NC=C4C5=CN(N=C5)CCO)N
• Alternate CAS: 1227939-82-3
• PubChem CID: 46207586
• MeSH Entry Terms: 1-(4-(4-amino-7-(1-(2-hydroxyethyl)-1H-pyrazol-4-yl)thieno(3,2-c)pyridin-3-yl)phenyl)-3-(3-fluorophenyl)urea;ABT-348;ilorasertib
• Molecular Weight: 488.5