Insulin Degludec, CAS No.844439-96-9

CAS: 844439-96-9 Cat. No.: I1492990 PubChem CID: 118984462
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GRADE & PURITY Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. PharmPure™ ? PharmPure™ — Aladdin's line of biopharmaceutical raw and starting materials. Use for pharma manufacturing inputs needing high purity and documentation. Lyophilized powder ? Lyophilized (freeze-dried) powder — gently dried to preserve activity and aid storage. Use for sensitive biologics reconstituted before use. ≥99% 大肠杆菌表达;Potency: ≥ 15 U/mg
Accession #
P01308
Expression system
E. coli
Endotoxin Concentration
<10 EU/mg
Bioactivity
≥15 U/mg
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Size
Deutschland (EU)
USA*
Price
Qty
1mg
I1492990-1mg
Auf Bestellung · 8–12 Wochen
60,65€
5mg
I1492990-5mg
Auf Bestellung · 8–12 Wochen
147,43€
10mg
I1492990-10mg
Auf Bestellung · 8–12 Wochen
234,20€
25mg
I1492990-25mg
Auf Bestellung · 8–12 Wochen
477,17€
50mg
I1492990-50mg
Auf Bestellung · 8–12 Wochen
737,49€
100mg
I1492990-100mg
Auf Bestellung · 8–12 Wochen
1.127,97€
250mg
I1492990-250mg
Auf Bestellung · 8–12 Wochen
1.735,39€
Enter a quantity for the sizes you want to add.
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Why this grade

Recombinant, PharmPure™, Lyophilized powder, ≥99%, 大肠杆菌表达;Potency: ≥ 15 U/mg Lyophilized powder,PharmPure™,Recombinant for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Insulin Degludec is an ultra‑long‑acting insulin analog used for research on hyperglycemia caused by type 1 and type 2 diabetes mellitus. The IC₅₀ value for insulin receptor binding is 19.59 nM (*in‑house assay data). It can be applied in research of type 1 and type 2 diabetes mellitus.

Structure:

Insulin degludec consists of two peptide chains. The A‑chain is identical to human insulin A‑chain with 21 amino‑acid residues. The B‑chain lacks threonine at position B30 compared with human insulin, containing 29 amino‑acid residues. The ε‑amino group of lysine at position B29 is conjugated to hexadecanedioic acid via a γ‑L‑glutamic acid linker.

Molecular formula: C₂₇₄H₄₁₁N₆₅O₈₁S₆  

Molecular weight: 6103.97

Sensitivity: Light‑sensitive; hygroscopic.

Solubility: Practically insoluble in water and absolute ethanol; freely soluble in dilute hydrochloric acid and dilute sodium hydroxide solutions.

Schematic Diagram: 

Specifications

Product Name
Insulin Degludec, CAS No.844439-96-9
Note
Lyophilized powder, PharmPure™, Recombinant
Spezifikationen & Reinheit
Recombinant, PharmPure™, Lyophilized powder, ≥99%, 大肠杆菌表达;Potency: ≥ 15 U/mg
Bioaktivität
≥15 U/mg
Endotoxin-Konzentration
<10 EU/mg
Sequenz
A-chain:Gly-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn B‑chain:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys
Beitritt #
Voraussichtliches Molekulargewicht
6103.97
CAS
844439-96-9
Product Line
biological_products
Lagerung und Versand
Konzentration
大肠杆菌表达;Potency: ≥ 15 U/mg
Storage
Protected from light,Store at -20°C,Desiccated,Avoid repeated freezing and thawing
Verschickt in
Ice chest + Ice pads
Stabilität und Lagerung
Store at -20℃ long term (24 months). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. Store in the dark. Desiccated.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Lösungsrechner
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