Irresistin-16 - Moligand™, ≥98% , CAS No.2624247-60-3

CAS: 2624247-60-3 Cat. No.: I611149 Summenformel: C₂₃H₁₉N₅ Molekulargewicht: 365.43

GRADE & PURITY Moligand™, ≥98%

Synonyms

IRS-16 | IRS16 | 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-([1,1'-biphenyl]-4-ylmethyl)- | IRS-16

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Übersicht

Irresistin-16, an SCH 79797 derivative, is a broad spectrum bactericidal antibiotic that is effective in both gram-positive and gram-negative bacteria and exhibits low frequency of resistance. Irresistin-16 act through interruption of bacterial folate metabolism and bacterial membrane integrity. It inhibits E. coli dihydrofolate reductase FolA. Irresistin-16 is effective in mouse gonorrhea infection model.

Specifications

Synonyme

IRS-16 | IRS16 | 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-([1,1'-biphenyl]-4-ylmethyl)- | IRS-16

Spezifikationen & Reinheit

Moligand™, ≥98%

Storage

Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Reinheit

≥98%

Namen und Kennungen

• Kanonisches Lächeln: Nc1nc(N)c2c(n1)ccc1c2ccn1Cc1ccc(cc1)c1ccccc1
• IUPAC Name: 7-[(4-phenylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine
• InChIKey: CKQXMSDRDDHCOR-UHFFFAOYSA-N
• INCHI: 1S/C23H19N5/c24-22-21-18-12-13-28(20(18)11-10-19(21)26-23(25)27-22)14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13H,14H2,(H4,24,25,26,27)
• Molekulargewicht: 365.43

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Klasse Benzene and substituted derivatives
      • Subclass Biphenyls and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Klasse: Benzene and substituted derivatives
• Subclass: Biphenyls and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Biphenyls and derivatives
• Alternative Parents: Quinazolinamines N-alkylindoles Indoles Aminopyrimidines and derivatives Substituted pyrroles Imidolactams Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Biphenyl - Quinazolinamine - N-alkylindole - Quinazoline - Indole - Indole or derivatives - Aminopyrimidine - Imidolactam - Substituted pyrrole - Pyrimidine - Heteroaromatic compound - Pyrrole - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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SLC2A1 Tchem Solute carrier family 2, facilitated glucose transporter member 1 (1 Activities)

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SLC2A1 Tchem Glucose transporter (14755 Activities)

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HepG2 (196354 Activities)

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Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Enterococcus faecium (13803 Activities)

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Plasmodium falciparum (966862 Activities)

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Enterobacter sp. (336 Activities)

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Wirkungsmechanismen