Name: Kavain (+/-) - 10mM in DMSO , CAS No.500-64-1
SKU: K424312
Availability: InStock

Kavain (+/-) - 10mM in DMSO , CAS No.500-64-1

CAS: 500-64-1 Cat. No.: K424312 Summenformel: C₁₄H₁₄O₃ Molekulargewicht: 230.3 Beilstein Registry Number: 177877

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Kavain (+/-) - 10mM in DMSO CAS No(500-64-1) by Aladdin Scientific

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GRADE & PURITY 10mM in DMSO

Synonyms

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht Specifications Namen und Kennungen Documentation Advanced Data Taxonomic Classification 3D-Struktur Zugehörige Ziele (menschlich) Zugehörige Ziele (nicht menschlich) Wirkungsmechanismen Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm) Chemische und physikalische Eigenschaften Lösungsrechner Bewertungen

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Übersicht

Kavain (+/-), a lipophilic kavapyrone, has been originally extracted from|Piper methysticum|. This compound has been shown to significantly antagonize dopamine depletion in murine striatal neurons. Additional studies report that Kavain (+/-) impairs vascular smooth muscle contraction via inhibition of Ca|+|channels, causing relaxation in precontracted murine ileum, airways, and aortic rings. Furthermore, at high concentrations, this agent has been noted to display neurotoxic characteristics.

Specifications

Synonyme

Spezifikationen & Reinheit

10mM in DMSO

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Namen und Kennungen

Pubchem Sid	528775977
Kanonisches Lächeln	COC1=CC(=O)OC(C1)C=CC2=CC=CC=C2
IUPAC Name	(2R)-4-methoxy-2-[(E)-2-phenylethenyl]-2,3-dihydropyran-6-one
InChIKey	XEAQIWGXBXCYFX-GUOLPTJISA-N
INCHI	1S/C14H14O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-8,10,12H,9H2,1H3/b8-7+/t12-/m0/s1
Isomere SMILES	COC1=CC(=O)O[C@H](C1)/C=C/C2=CC=CC=C2
WGK Deutschland	3
RTECS	UQ0518000
Molekulargewicht	230.3
Beilstein	177877
Reaxy-Rn	84886
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=84886&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

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🔬 Specification Sheet

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Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Phenylpropanoids and polyketides
  - Klasse Kavalactones

Kingdom	Organic compounds
Superclass	Phenylpropanoids and polyketides
Klasse	Kavalactones
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Kavalactones
Alternative Parents	Styrenes Dihydropyranones Vinylogous esters Enoate esters Lactones Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Kavalactone - Styrene - Dihydropyranone - Monocyclic benzene moiety - Pyran - Benzenoid - Alpha,beta-unsaturated carboxylic ester - Enoate ester - Vinylogous ester - Lactone - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organoheterocyclic compound - Oxacycle - Carbonyl group - Hydrocarbon derivative - Organooxygen compound - Organic oxide - Organic oxygen compound - Aromatic heteromonocyclic compound
Beschreibung	This compound belongs to the class of organic compounds known as kavalactones. These are lactones, which is structurally characterized by a benzene ring and a pyranone moiety, linked to each other to form a 4-methoxy-6-(2-phenylethyl)-2H-pyran-2-one skeleton.
External Descriptors	Polyketides - alpha-Pyrones
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D-Struktur

Zugehörige Ziele (menschlich)

RXRA Tclin Retinoid X receptor alpha (3637 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

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GMNN Tbio Geminin (128009 Activities)

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ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)

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TARDBP Tchem TAR DNA-binding protein 43 (40113 Activities)

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ampC Beta-lactamase AmpC (62480 Activities)

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Ppard Peroxisome proliferator-activated receptor delta (358 Activities)

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Echinochloa crus-galli (3685 Activities)

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Fusarium solani (1274 Activities)

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Plasmodium falciparum (966862 Activities)

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Fusarium oxysporum (3998 Activities)

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Trichoderma viride (1263 Activities)

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PC-12 (7051 Activities)

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Lactuca sativa (1092 Activities)

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Colletotrichum gloeosporioides (560 Activities)

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

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PA Polymerase acidic protein (806 Activities)

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Rorc Nuclear receptor ROR-gamma (89407 Activities)

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Nr1i2 Nuclear receptor subfamily 1 group I member 2 (14 Activities)

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Wirkungsmechanismen

Zertifikate (CoA, COO, BSE/TSE und Analyse-Diagramm)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	Datum	Artikel
H2408032	Certificate of Analysis	Jun 03, 2026	K424312

Chemische und physikalische Eigenschaften

Brechungsindex	n20D1.57
Siedepunkt (°C)	432.64° C at 760 mmHg (Predicted)
Schmelzpunkt (°C)	105.5° C
Molekulargewicht	230.260 g/mol
XLogP3	2.500
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	230.094 Da
Monoisotopic Mass	230.094 Da
Topological Polar Surface Area	35.500 Å²
Heavy Atom Count	17
Formal Charge	0
Complexity	324.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

Lösungsrechner

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Kavain (+/-) - 10mM in DMSO , CAS No.500-64-1

Why this grade

Storage & shipping

Quality documents

Literature proof

Übersicht

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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