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Is CD45.1/ CD45.2 a CD45?
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Is CD45.1/ CD45.2 a CD45?
No. CD45.1 and CD45.2 are forms of subtype markers on the surface of immune cells and are members of the CD45 (cluster of differentiation 45) family.CD45 is a receptor-type protein tyrosine phosphatase that is widely expressed in a variety of immune cells, such as T cells, B cells, macrophages, etc. There are several subtypes of CD45, including CD45.1 and CD45.2. These include CD45.1 and CD45.2, which are mainly determined by different alleles on the CD45 gene. The introduction of CD45.1 or CD45.2 isoforms can be used to distinguish between cells of different origins.
Mouse strains expressing CD45.1 include FVB, RIII, SJL/J, STS/A, DA, etc., and mouse strains expressing CD45.2 include AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129 etc.
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