L-Arginine - Moligand™, 10mM in Water , CAS No.74-79-3

CAS: 74-79-3 Cat. No.: L425810 Summenformel: C₆H₁₄N₄O₂ Molekulargewicht: 174.20 g/mol Beilstein Registry Number: 1725413 EG-Nummer: 200-811-1

GRADE & PURITY Moligand™, 10mM in Water

Synonyms

L-arginine|arginine|74-79-3|L-(+)-Arginine|L(+)-Arginine|L-Arg|(S)-2-Amino-5-guanidinopentanoic acid|H-Arg-OH|(L)-Arginine|Arginina|ARGININE, L-|Arginine (VAN)|L-Arginin|Argininum [INN-Latin]|Arginina [INN-Spanish]|L-Ornithine, N5-(aminoiminomethyl)-|L-al

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

L-Arginine is an essential amino acid and precursor of nitric oxide synthesis that induces vasodilation in vivo. Nitric oxide potentiates insulin-mediated glucose uptake through the increase in blood flow.
A precursor of nitric oxide synthesis that induces vasodilation

Specifications

Synonyme

L-arginine | arginine | 74-79-3 | L-(+)-Arginine | L(+)-Arginine | L-Arg | (S)-2-Amino-5-guanidinopentanoic acid | H-Arg-OH | (L)-Arginine | Arginina | ARGININE, L- | Arginine (VAN) | L-Arginin | Argininum [INN-Latin] | Arginina [INN-Spanish] | L-Ornithine, N5-(aminoiminomethyl)- | L-al

Spezifikationen & Reinheit

Moligand™, 10mM in Water

Biochemische und physiologische Mechanismen

Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.Precursor to nitric oxide synthesis. Amino acid implicated in neurotransmission, immune defences and

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Aktionsart

ACTIVATOR

Namen und Kennungen

• Kanonisches Lächeln: C(CC(C(=O)O)N)CN=C(N)N
• IUPAC Name: (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid
• InChIKey: ODKSFYDXXFIFQN-BYPYZUCNSA-N
• INCHI: 1S/C6H14N4O2/c7-4(5(11)12)2-1-3-10-6(8)9/h4H,1-3,7H2,(H,11,12)(H4,8,9,10)/t4-/m0/s1
• Isomere SMILES: C(C[C@@H](C(=O)O)N)CN=C(N)N
• WGK Deutschland: 1
• RTECS: CF1934200
• Molekulargewicht: 174.20 g/mol
• Beilstein: 1725413
• Reaxy-Rn: 2090768
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2090768&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Ebene5 Amino acids and derivatives
          • Ebene6 Alpha amino acids and derivatives
            • Ebene7 Alpha amino acids
              • Ebene8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Fatty acids and conjugates Guanidines Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidamides Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Fatty acid - Guanidine - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Carboximidamide - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Amine - Hydrocarbon derivative - Organic oxide - Primary amine - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Primary aliphatic amine - Organic oxygen compound - Organic nitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Common amino acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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GPRC6A Tchem G-protein coupled receptor family C group 6 member A (1 Activities)

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CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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ACE Tclin Angiotensin-converting enzyme (1423 Activities)

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TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

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GLA Tclin Alpha-galactosidase A (5444 Activities)

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NOS1 Tchem Nitric-oxide synthase, brain (1786 Activities)

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CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)

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NFKB1 Tclin Nuclear factor NF-kappa-B p105 subunit (1459 Activities)

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NOS3 Tchem Nitric-oxide synthase, endothelial (1452 Activities)

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CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

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TPSAB1 Tclin Tryptase beta-1 (295 Activities)

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CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)

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CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

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Homo sapiens (32628 Activities)

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FEN1 Tchem Flap endonuclease 1 (12055 Activities)

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SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)

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POLI Tchem DNA polymerase iota (116820 Activities)

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DDAH1 Tchem N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (231 Activities)

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

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CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

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Nos2 Nitric oxide synthase, inducible (3573 Activities)

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Hdac6 Histone deacetylase 6 (222 Activities)

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Staphylococcus aureus (210822 Activities)

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Escherichia coli (133304 Activities)

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Saccharomyces cerevisiae (19171 Activities)

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Mus musculus (284745 Activities)

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Rattus norvegicus (775804 Activities)

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Botrytis cinerea (4183 Activities)

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GH3 (79 Activities)

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lef Anthrax lethal factor (7585 Activities)

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pfk 6-phospho-1-fructokinase (7870 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

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Bacillus spizizenii (1898 Activities)

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Amphibalanus improvisus (34 Activities)

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Felid alphaherpesvirus 1 (460 Activities)

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Solanum lycopersicum (493 Activities)

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Plasma (328 Activities)

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Slc22a5 Solute carrier family 22 member 5 (44 Activities)

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ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)

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Slc22a4 Solute carrier family 22 member 4 (11 Activities)

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Slc16a10 Monocarboxylate transporter 10 (73 Activities)

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Gprc6a G-protein coupled receptor family C group 6 member A (53 Activities)

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SARS-CoV-2 (38078 Activities)

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Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Empfindlichkeit: Air sensitive
• Spezifische Drehung [α]: 27 ° (C=8, 6mol/L HCl)
• Schmelzpunkt (°C): 222 °C
• Molekulargewicht: 174.200 g/mol
• XLogP3: -4.200
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 174.112 Da
• Monoisotopic Mass: 174.112 Da
• Topological Polar Surface Area: 128.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 176.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1