Determine the necessary mass, volume, or concentration for preparing a solution.
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≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature,Argon charged Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
L-4-Thiazolidinecarboxylic acid has been used in peptide coupling reactions.
| Pubchem Sid | 504756175 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504756175 |
| Canonical Smiles | C1C(NCS1)C(=O)O |
| IUPAC Name | (4R)-1,3-thiazolidine-4-carboxylic acid |
| InChIKey | DZLNHFMRPBPULJ-VKHMYHEASA-N |
| INCHI | 1S/C4H7NO2S/c6-4(7)3-1-8-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1 |
| Isomeric SMILES | C1[C@H](NCS1)C(=O)O |
| WGK Germany | 3 |
| RTECS | XJ5425500 |
| PubChem CID | 93176 |
| Molecular Weight | 133.17 |
| Beilstein | 81065 |
| Reaxy-Rn | 81065 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids |
| Direct Parent | L-alpha-amino acids |
| Alternative Parents | Thiazolidines Amino acids Thiohemiaminal derivatives Monocarboxylic acids and derivatives Dialkylthioethers Dialkylamines Carboxylic acids Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | L-alpha-amino acid - Thiazolidine - Amino acid - Carboxylic acid - Secondary aliphatic amine - Monocarboxylic acid or derivatives - Secondary amine - Thioether - Hemithioaminal - Dialkylthioether - Organoheterocyclic compound - Azacycle - Organic nitrogen compound - Amine - Carbonyl group - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxide - Aliphatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom. |
| External Descriptors | thiazolidinemonocarboxylic acid - thioproline |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 19, 2025 | T137734 | |
| Certificate of Analysis | Nov 12, 2025 | T137734 | |
| Certificate of Analysis | Nov 12, 2025 | T137734 | |
| Certificate of Analysis | Oct 13, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Sep 08, 2025 | T137734 | |
| Certificate of Analysis | Dec 31, 2024 | T137734 | |
| Certificate of Analysis | Dec 31, 2024 | T137734 | |
| Certificate of Analysis | Jan 11, 2023 | T137734 |
| Sensitivity | Air sensitive |
|---|---|
| Specific Rotation[α] | -200° (C=1,1mol/L NaOH sol.) |
| Melt Point(°C) | 192-200°C |
| Molecular Weight | 133.170 g/mol |
| XLogP3 | -2.300 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 133.02 Da |
| Monoisotopic Mass | 133.02 Da |
| Topological Polar Surface Area | 74.600 Ų |
| Heavy Atom Count | 8 |
| Formal Charge | 0 |
| Complexity | 106.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |