Lafutidine - 10mM in DMSO , Histamine H2 receptor antagonist, CAS No.118288-08-7, Histamine H2 receptor antagonist

CAS: 118288-08-7 Cat. No.: L409230 Summenformel: C₂₂H₂₉N₃O₄S Molekulargewicht: 431.55 EG-Nummer: 601-513-8 PubChem CID: 5282136

GRADE & PURITY 10mM in DMSO

Synonyms

FRG-8813 | (+)​-2-​[(2-​furanylmethyl)​sulfinyl]​-​N-​[(2Z)​-​4-​[[4-​(1-​piperidinylmethyl)​-​2-​pyridinyl]​oxy]​-​2-​buten-​1-​yl]​-acetamide

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Übersicht

Information

Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.
In vitro

In vivo

Cell Data

cell lines：BT474 cell line and the primary breast cancer cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Synonyme

FRG-8813 | (+)​-2-​[(2-​furanylmethyl)​sulfinyl]​-​N-​[(2Z)​-​4-​[[4-​(1-​piperidinylmethyl)​-​2-​pyridinyl]​oxy]​-​2-​buten-​1-​yl]​-acetamide

Spezifikationen & Reinheit

10mM in DMSO

Biochemische und physiologische Mechanismen

Lafutidine (FRG-8813), a newly developed histamine H(2)-receptor antagonist, inhibits gastric acid secretion.

Storage

Store at -80°C

Verschickt in

Dry ice packs + Cold packs

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

ANTAGONIST

Mechanismus der Wirkung

Histamine H2 receptor antagonist

Produkteigenschaften

• ALogP: 1.4

Namen und Kennungen

• Isomere SMILES: C1CCN(CC1)CC2=CC(=NC=C2)OC/C=C\CNC(=O)CS(=O)CC3=CC=CO3
• RTECS: AC2957000
• PubChem CID: 5282136
• Molekulargewicht: 431.55

Chemische und physikalische Eigenschaften

• Löslichkeit: Solubility (25°C) In vitro DMSO: 55 mg/mL (198.35 mM); Water: Insoluble; Ethanol: Insoluble
• Schmelzpunkt (°C): 99 °C

Referenzen

1. Guodong Shan, Xiuqin Fan, Qingcheng Wang, Li Zhang, Lijun Ge, Weibo Lu, Jing Xue, Kang Chen, Zejun Wang, Qing Shen.  (2025)  Development of a Captiva EMR-lipid clean-up and LC-MS/MS methodology for detecting H2 receptor antagonists in functional foods and food-medicine homology materials.  Applied Food Research,      [PMID:] [10.1016/j.afres.2025.100772]